<italic toggle="yes">aroA</italic>-Deficient <named-content content-type="genus-species">Salmonella enterica</named-content> Serovar Typhimurium Is More Than a Metabolically Attenuated Mutant

<italic toggle="yes">aroA</italic>-Deficient <named-content content-type="genus-species">Salmonella enterica</named-content> Serovar Typhimurium Is More Than a Metabolically Attenuated Mutant

ABSTRACT Recombinant attenuated Salmonella enterica serovar Typhimurium strains are believed to act as powerful live vaccine carriers that are able to elicit protection against various pathogens. Auxotrophic mutations, such as a deletion of aroA, are commonly introduced into such bacteria for attenu...

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Autores principales: Sebastian Felgner, Michael Frahm, Dino Kocijancic, Manfred Rohde, Denitsa Eckweiler, Agata Bielecka, Emilio Bueno, Felipe Cava, Wolf-Rainer Abraham, Roy Curtiss, Susanne Häussler, Marc Erhardt, Siegfried Weiss
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2016
Materias:
Microbiology
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Acceso en línea:https://doaj.org/article/b28681446d39498e87e4324eb3ecfd84
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