Normalizing RNA-sequencing data by modeling hidden covariates with prior knowledge.

Normalizing RNA-sequencing data by modeling hidden covariates with prior knowledge.

Transcriptomic assays that measure expression levels are widely used to study the manifestation of environmental or genetic variations in cellular processes. RNA-sequencing in particular has the potential to considerably improve such understanding because of its capacity to assay the entire transcri...

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Autores principales: Sara Mostafavi, Alexis Battle, Xiaowei Zhu, Alexander E Urban, Douglas Levinson, Stephen B Montgomery, Daphne Koller
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/b2924a71dadf489e8607ad370e407a38
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