Relaxed Substrate Specificity Leads to Extensive tRNA Mischarging by <named-content content-type="genus-species">Streptococcus pneumoniae</named-content> Class I and Class II Aminoacyl-tRNA Synthetases
ABSTRACT Aminoacyl-tRNA synthetases provide the first step in protein synthesis quality control by discriminating cognate from noncognate amino acid and tRNA substrates. While substrate specificity is enhanced in many instances by cis- and trans-editing pathways, it has been revealed that in organis...
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| Main Authors: | , |
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| Format: | article |
| Language: | EN |
| Published: |
American Society for Microbiology
2014
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| Subjects: | |
| Online Access: | https://doaj.org/article/b29f60d7c9d942bc9eeb028ae034436b |
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