Alcohol and Dementia – What is the Link? A Systematic Review
Caspar Wiegmann, 1 Inge Mick, 1 Eva J Brandl, 1 Andreas Heinz, 1, 2 Stefan Gutwinski 1 1Department of Psychiatry and Psychotherapy, Psychiatric Hospital of Charité at St. Hedwig Hospital, Berlin, Germany; 2Department of Psychiatry and Psychotherapy, Charité University Medicin...
Guardado en:
| Autores principales: | , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Dove Medical Press
2020
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/b2a008113ce446e8a9fbe6d5518dd5d3 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:b2a008113ce446e8a9fbe6d5518dd5d3 |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:b2a008113ce446e8a9fbe6d5518dd5d32021-12-02T08:49:35ZAlcohol and Dementia – What is the Link? A Systematic Review1178-2021https://doaj.org/article/b2a008113ce446e8a9fbe6d5518dd5d32020-01-01T00:00:00Zhttps://www.dovepress.com/alcohol-and-dementia-what-is-the-link-a-systematic-review-peer-reviewed-article-NDThttps://doaj.org/toc/1178-2021Caspar Wiegmann, 1 Inge Mick, 1 Eva J Brandl, 1 Andreas Heinz, 1, 2 Stefan Gutwinski 1 1Department of Psychiatry and Psychotherapy, Psychiatric Hospital of Charité at St. Hedwig Hospital, Berlin, Germany; 2Department of Psychiatry and Psychotherapy, Charité University Medicine Berlin, Berlin, GermanyCorrespondence: Caspar WiegmannPsychiatrische Universitätsklinik der Charité im St. Hedwig-Krankenhaus, Große Hamburger Str. 5-11, Berlin-Mitte 10115, GermanyTel +49 30 2311 2500Email caspar.wiegmann@charite.deBackground: Dementia is a globally increasing health issue and since no cure is currently available, prevention is crucial. The consumption of alcohol is a controversially discussed risk factor for dementia. While many previously published epidemiological studies reported a risk reduction by light to moderate alcohol consumption, there is no persuasive model of an underlying biochemical mechanism. The purpose of this article is to review current models on alcohol neurotoxicity and dementia and to analyze and compare studies focusing on the epidemiological link between alcohol consumption and the risk of dementia.Methods: The electronic database Pubmed was searched for studies published between 1994 and 2019 concerning the topic.Results: Available epidemiological studies are not sufficient to verify a protective effect of alcohol on dementia development.Keywords: alcohol neurotoxicity, Alzheimer’s disease, vascular dementia, Korsakoff´s syndromeWiegmann CMick IBrandl EJHeinz AGutwinski SDove Medical Pressarticlealcohol neurotoxicityalzheimer’s diseasevascular dementiakorsakoff´s syndromeNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol Volume 16, Pp 87-99 (2020) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
alcohol neurotoxicity alzheimer’s disease vascular dementia korsakoff´s syndrome Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 |
| spellingShingle |
alcohol neurotoxicity alzheimer’s disease vascular dementia korsakoff´s syndrome Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Wiegmann C Mick I Brandl EJ Heinz A Gutwinski S Alcohol and Dementia – What is the Link? A Systematic Review |
| description |
Caspar Wiegmann, 1 Inge Mick, 1 Eva J Brandl, 1 Andreas Heinz, 1, 2 Stefan Gutwinski 1 1Department of Psychiatry and Psychotherapy, Psychiatric Hospital of Charité at St. Hedwig Hospital, Berlin, Germany; 2Department of Psychiatry and Psychotherapy, Charité University Medicine Berlin, Berlin, GermanyCorrespondence: Caspar WiegmannPsychiatrische Universitätsklinik der Charité im St. Hedwig-Krankenhaus, Große Hamburger Str. 5-11, Berlin-Mitte 10115, GermanyTel +49 30 2311 2500Email caspar.wiegmann@charite.deBackground: Dementia is a globally increasing health issue and since no cure is currently available, prevention is crucial. The consumption of alcohol is a controversially discussed risk factor for dementia. While many previously published epidemiological studies reported a risk reduction by light to moderate alcohol consumption, there is no persuasive model of an underlying biochemical mechanism. The purpose of this article is to review current models on alcohol neurotoxicity and dementia and to analyze and compare studies focusing on the epidemiological link between alcohol consumption and the risk of dementia.Methods: The electronic database Pubmed was searched for studies published between 1994 and 2019 concerning the topic.Results: Available epidemiological studies are not sufficient to verify a protective effect of alcohol on dementia development.Keywords: alcohol neurotoxicity, Alzheimer’s disease, vascular dementia, Korsakoff´s syndrome |
| format |
article |
| author |
Wiegmann C Mick I Brandl EJ Heinz A Gutwinski S |
| author_facet |
Wiegmann C Mick I Brandl EJ Heinz A Gutwinski S |
| author_sort |
Wiegmann C |
| title |
Alcohol and Dementia – What is the Link? A Systematic Review |
| title_short |
Alcohol and Dementia – What is the Link? A Systematic Review |
| title_full |
Alcohol and Dementia – What is the Link? A Systematic Review |
| title_fullStr |
Alcohol and Dementia – What is the Link? A Systematic Review |
| title_full_unstemmed |
Alcohol and Dementia – What is the Link? A Systematic Review |
| title_sort |
alcohol and dementia – what is the link? a systematic review |
| publisher |
Dove Medical Press |
| publishDate |
2020 |
| url |
https://doaj.org/article/b2a008113ce446e8a9fbe6d5518dd5d3 |
| work_keys_str_mv |
AT wiegmannc alcoholanddementiandashwhatisthelinkasystematicreview AT micki alcoholanddementiandashwhatisthelinkasystematicreview AT brandlej alcoholanddementiandashwhatisthelinkasystematicreview AT heinza alcoholanddementiandashwhatisthelinkasystematicreview AT gutwinskis alcoholanddementiandashwhatisthelinkasystematicreview |
| _version_ |
1718398384973283328 |