The association between aids related stigma and major depressive disorder among HIV-positive individuals in Uganda.

<h4>Background</h4>Major depressive disorder in people living with HIV/AIDS (PLWHA) is common and may be associated with a number of factors, including AIDS-related stigma, decreased CD4 levels, increased opportunistic infections and sociodemographic variables. The extent to which AIDS-r...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Dickens Akena, Seggane Musisi, John Joska, Dan J Stein
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2012
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/b2a8170aba3c4dc49595ddcd77314db3
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:b2a8170aba3c4dc49595ddcd77314db3
record_format	dspace
spelling	oai:doaj.org-article:b2a8170aba3c4dc49595ddcd77314db32021-11-18T08:07:32ZThe association between aids related stigma and major depressive disorder among HIV-positive individuals in Uganda.1932-620310.1371/journal.pone.0048671https://doaj.org/article/b2a8170aba3c4dc49595ddcd77314db32012-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23209556/pdf/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Background</h4>Major depressive disorder in people living with HIV/AIDS (PLWHA) is common and may be associated with a number of factors, including AIDS-related stigma, decreased CD4 levels, increased opportunistic infections and sociodemographic variables. The extent to which AIDS-related stigma is associated with major depressive disorder among PLWHA has not been well studied in sub-Saharan Africa. The objective of this study was to examine the associations between major depressive disorder, AIDS-related stigma, immune status, and sociodemographic variables with the aim of making recommendations that can guide clinicians.<h4>Methods</h4>We assessed 368 PLWHA for major depressive disorder, as well as for potentially associated factors, including AIDS-related stigma, CD4 levels, presence of opportunistic infections, and sociodemographic variables.<h4>Results</h4>The prevalence of major depressive disorder was 17.4%, while 7.9% of the participants had AIDS related stigma. At multivariable analysis, major depressive disorder was significantly associated with AIDS-related stigma [OR = 1.65, CI (1.20-2.26)], a CD4 count of ≥200 [OR 0.52 CI (0.27-0.99)], and being of younger age [0.95, CI (0.92-0.98).<h4>Conclusions</h4>Due to the high burden of major depressive disorder, and its association with AIDS related stigma, routine screening of PLWHA for both conditions is recommended. However, more research is required to understand this association.Dickens AkenaSeggane MusisiJohn JoskaDan J SteinPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 7, Iss 11, p e48671 (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Dickens Akena Seggane Musisi John Joska Dan J Stein The association between aids related stigma and major depressive disorder among HIV-positive individuals in Uganda.
description	<h4>Background</h4>Major depressive disorder in people living with HIV/AIDS (PLWHA) is common and may be associated with a number of factors, including AIDS-related stigma, decreased CD4 levels, increased opportunistic infections and sociodemographic variables. The extent to which AIDS-related stigma is associated with major depressive disorder among PLWHA has not been well studied in sub-Saharan Africa. The objective of this study was to examine the associations between major depressive disorder, AIDS-related stigma, immune status, and sociodemographic variables with the aim of making recommendations that can guide clinicians.<h4>Methods</h4>We assessed 368 PLWHA for major depressive disorder, as well as for potentially associated factors, including AIDS-related stigma, CD4 levels, presence of opportunistic infections, and sociodemographic variables.<h4>Results</h4>The prevalence of major depressive disorder was 17.4%, while 7.9% of the participants had AIDS related stigma. At multivariable analysis, major depressive disorder was significantly associated with AIDS-related stigma [OR = 1.65, CI (1.20-2.26)], a CD4 count of ≥200 [OR 0.52 CI (0.27-0.99)], and being of younger age [0.95, CI (0.92-0.98).<h4>Conclusions</h4>Due to the high burden of major depressive disorder, and its association with AIDS related stigma, routine screening of PLWHA for both conditions is recommended. However, more research is required to understand this association.
format	article
author	Dickens Akena Seggane Musisi John Joska Dan J Stein
author_facet	Dickens Akena Seggane Musisi John Joska Dan J Stein
author_sort	Dickens Akena
title	The association between aids related stigma and major depressive disorder among HIV-positive individuals in Uganda.
title_short	The association between aids related stigma and major depressive disorder among HIV-positive individuals in Uganda.
title_full	The association between aids related stigma and major depressive disorder among HIV-positive individuals in Uganda.
title_fullStr	The association between aids related stigma and major depressive disorder among HIV-positive individuals in Uganda.
title_full_unstemmed	The association between aids related stigma and major depressive disorder among HIV-positive individuals in Uganda.
title_sort	association between aids related stigma and major depressive disorder among hiv-positive individuals in uganda.
publisher	Public Library of Science (PLoS)
publishDate	2012
url	https://doaj.org/article/b2a8170aba3c4dc49595ddcd77314db3
work_keys_str_mv	AT dickensakena theassociationbetweenaidsrelatedstigmaandmajordepressivedisorderamonghivpositiveindividualsinuganda AT segganemusisi theassociationbetweenaidsrelatedstigmaandmajordepressivedisorderamonghivpositiveindividualsinuganda AT johnjoska theassociationbetweenaidsrelatedstigmaandmajordepressivedisorderamonghivpositiveindividualsinuganda AT danjstein theassociationbetweenaidsrelatedstigmaandmajordepressivedisorderamonghivpositiveindividualsinuganda AT dickensakena associationbetweenaidsrelatedstigmaandmajordepressivedisorderamonghivpositiveindividualsinuganda AT segganemusisi associationbetweenaidsrelatedstigmaandmajordepressivedisorderamonghivpositiveindividualsinuganda AT johnjoska associationbetweenaidsrelatedstigmaandmajordepressivedisorderamonghivpositiveindividualsinuganda AT danjstein associationbetweenaidsrelatedstigmaandmajordepressivedisorderamonghivpositiveindividualsinuganda
_version_	1718422188422332416

The association between aids related stigma and major depressive disorder among HIV-positive individuals in Uganda.

Ejemplares similares