A molecular portrait of microsatellite instability across multiple cancers

Some cancers with DNA mismatch repair deficiency display microsatellite instability. Here the authors analyse twenty three cancer types at the exome and whole-genome level, and identify loci with recurrent microsatellite instability that could be used to identify patients who would benefit from immu...

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Autores principales:	Isidro Cortes-Ciriano, Sejoon Lee, Woong-Yang Park, Tae-Min Kim, Peter J. Park
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b2b03e49a2a0482ab2a3e3eccf1875e9
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id	oai:doaj.org-article:b2b03e49a2a0482ab2a3e3eccf1875e9
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spelling	oai:doaj.org-article:b2b03e49a2a0482ab2a3e3eccf1875e92021-12-02T15:38:38ZA molecular portrait of microsatellite instability across multiple cancers10.1038/ncomms151802041-1723https://doaj.org/article/b2b03e49a2a0482ab2a3e3eccf1875e92017-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms15180https://doaj.org/toc/2041-1723Some cancers with DNA mismatch repair deficiency display microsatellite instability. Here the authors analyse twenty three cancer types at the exome and whole-genome level, and identify loci with recurrent microsatellite instability that could be used to identify patients who would benefit from immunotherapy.Isidro Cortes-CirianoSejoon LeeWoong-Yang ParkTae-Min KimPeter J. ParkNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Isidro Cortes-Ciriano Sejoon Lee Woong-Yang Park Tae-Min Kim Peter J. Park A molecular portrait of microsatellite instability across multiple cancers
description	Some cancers with DNA mismatch repair deficiency display microsatellite instability. Here the authors analyse twenty three cancer types at the exome and whole-genome level, and identify loci with recurrent microsatellite instability that could be used to identify patients who would benefit from immunotherapy.
format	article
author	Isidro Cortes-Ciriano Sejoon Lee Woong-Yang Park Tae-Min Kim Peter J. Park
author_facet	Isidro Cortes-Ciriano Sejoon Lee Woong-Yang Park Tae-Min Kim Peter J. Park
author_sort	Isidro Cortes-Ciriano
title	A molecular portrait of microsatellite instability across multiple cancers
title_short	A molecular portrait of microsatellite instability across multiple cancers
title_full	A molecular portrait of microsatellite instability across multiple cancers
title_fullStr	A molecular portrait of microsatellite instability across multiple cancers
title_full_unstemmed	A molecular portrait of microsatellite instability across multiple cancers
title_sort	molecular portrait of microsatellite instability across multiple cancers
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/b2b03e49a2a0482ab2a3e3eccf1875e9
work_keys_str_mv	AT isidrocortesciriano amolecularportraitofmicrosatelliteinstabilityacrossmultiplecancers AT sejoonlee amolecularportraitofmicrosatelliteinstabilityacrossmultiplecancers AT woongyangpark amolecularportraitofmicrosatelliteinstabilityacrossmultiplecancers AT taeminkim amolecularportraitofmicrosatelliteinstabilityacrossmultiplecancers AT peterjpark amolecularportraitofmicrosatelliteinstabilityacrossmultiplecancers AT isidrocortesciriano molecularportraitofmicrosatelliteinstabilityacrossmultiplecancers AT sejoonlee molecularportraitofmicrosatelliteinstabilityacrossmultiplecancers AT woongyangpark molecularportraitofmicrosatelliteinstabilityacrossmultiplecancers AT taeminkim molecularportraitofmicrosatelliteinstabilityacrossmultiplecancers AT peterjpark molecularportraitofmicrosatelliteinstabilityacrossmultiplecancers
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A molecular portrait of microsatellite instability across multiple cancers

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