Gene expression signature-based screening identifies new broadly effective influenza a antivirals.

Classical antiviral therapies target viral proteins and are consequently subject to resistance. To counteract this limitation, alternative strategies have been developed that target cellular factors. We hypothesized that such an approach could also be useful to identify broad-spectrum antivirals. Th...

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Autores principales: Laurence Josset, Julien Textoris, Béatrice Loriod, Olivier Ferraris, Vincent Moules, Bruno Lina, Catherine N'guyen, Jean-Jacques Diaz, Manuel Rosa-Calatrava
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
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Acceso en línea:https://doaj.org/article/b2b2b357452843a6b40cf26b8132ea4b
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