Vascular endothelial growth factor-receptor 1 inhibition aggravates diabetic nephropathy through eNOS signaling pathway in db/db mice.

Vascular endothelial growth factor-receptor 1 inhibition aggravates diabetic nephropathy through eNOS signaling pathway in db/db mice.

The manipulation of vascular endothelial growth factor (VEGF)-receptors (VEGFRs) in diabetic nephropathy is as controversial as issue as ever. It is known to be VEGF-A and VEGFR2 that regulate most of the cellular actions of VEGF in experimental diabetic nephropathy. On the other hand, such factors...

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Main Authors: Keun Suk Yang, Ji Hee Lim, Tae Woo Kim, Min Young Kim, Yaeni Kim, Sungjin Chung, Seok Joon Shin, Beom Soon Choi, Hyung Wook Kim, Yong-Soo Kim, Yoon Sik Chang, Hye Won Kim, Cheol Whee Park
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2014
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/b2b761aa88bb4163a34a1ead5bbd8f2d
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https://doaj.org/article/b2b761aa88bb4163a34a1ead5bbd8f2d

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