In vivo and in vitro analysis of topographic changes secondary to DSAEK venting incisions

Majid Moshirfar, Monette T Lependu, Dane Church, Marcus C Neuffer John A Moran Eye Center, University of Utah, Salt Lake City, UT, USA Introduction: Descemet&rsquo;s stripping automated endothelial keratoplasty (DSAEK) venting incisions may induce irregular corneal astigmatism. The study exa...

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Autores principales:	Church D, Lependu MT, Moshirfar M, Neuffer MC
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2011
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/b2bfecd43e0a41db8555b11e0890f670
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spelling	oai:doaj.org-article:b2bfecd43e0a41db8555b11e0890f6702021-12-02T00:18:37ZIn vivo and in vitro analysis of topographic changes secondary to DSAEK venting incisions1177-54671177-5483https://doaj.org/article/b2bfecd43e0a41db8555b11e0890f6702011-08-01T00:00:00Zhttp://www.dovepress.com/in-vivo-and-in-vitro-analysis-of-topographic-changes-secondary-to-dsae-a8153https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Majid Moshirfar, Monette T Lependu, Dane Church, Marcus C Neuffer John A Moran Eye Center, University of Utah, Salt Lake City, UT, USA Introduction: Descemet&rsquo;s stripping automated endothelial keratoplasty (DSAEK) venting incisions may induce irregular corneal astigmatism. The study examines in vivo and in vitro astigmatic effects of venting incisions. Patients and methods: In vivo analysis examined eleven eyes of eleven patients who had received DSAEK with venting incisions. A chart review of the eleven eyes including assessment of pre and postoperative refraction and topography was performed. In vitro analysis examined three cadaver eyes which received topographic imaging followed by venting incisions at 4 mm, 6 mm, and 7 mm optical zones. Topographic imaging was then performed again after the incisions. Results: Postoperative topographies of eleven eyes demonstrated localized flattening at incision sites and cloverleaf pattern astigmatism. There was a significant difference in corneal irregularity measurement (P = 0.03), but no significant difference in shape factor or change of topographic cylinder. The cloverleaf pattern was found in cadaver eyes with incisions placed at 4 mm and 6 mm optical zones but not at the 7 mm zone. Conclusion: DSAEK venting incisions can cause irregular corneal astigmatism that may affect visual outcomes. The authors recommend placement of venting incisions near the 7 mm optical zone. Keywords: DSAEK, venting incisions, endothelial keratoplasty, astigmatism, endothelium, endothelial transplantChurch DLependu MTMoshirfar MNeuffer MCDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2011, Iss default, Pp 1195-1199 (2011)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Church D Lependu MT Moshirfar M Neuffer MC In vivo and in vitro analysis of topographic changes secondary to DSAEK venting incisions
description	Majid Moshirfar, Monette T Lependu, Dane Church, Marcus C Neuffer John A Moran Eye Center, University of Utah, Salt Lake City, UT, USA Introduction: Descemet&rsquo;s stripping automated endothelial keratoplasty (DSAEK) venting incisions may induce irregular corneal astigmatism. The study examines in vivo and in vitro astigmatic effects of venting incisions. Patients and methods: In vivo analysis examined eleven eyes of eleven patients who had received DSAEK with venting incisions. A chart review of the eleven eyes including assessment of pre and postoperative refraction and topography was performed. In vitro analysis examined three cadaver eyes which received topographic imaging followed by venting incisions at 4 mm, 6 mm, and 7 mm optical zones. Topographic imaging was then performed again after the incisions. Results: Postoperative topographies of eleven eyes demonstrated localized flattening at incision sites and cloverleaf pattern astigmatism. There was a significant difference in corneal irregularity measurement (P = 0.03), but no significant difference in shape factor or change of topographic cylinder. The cloverleaf pattern was found in cadaver eyes with incisions placed at 4 mm and 6 mm optical zones but not at the 7 mm zone. Conclusion: DSAEK venting incisions can cause irregular corneal astigmatism that may affect visual outcomes. The authors recommend placement of venting incisions near the 7 mm optical zone. Keywords: DSAEK, venting incisions, endothelial keratoplasty, astigmatism, endothelium, endothelial transplant
format	article
author	Church D Lependu MT Moshirfar M Neuffer MC
author_facet	Church D Lependu MT Moshirfar M Neuffer MC
author_sort	Church D
title	In vivo and in vitro analysis of topographic changes secondary to DSAEK venting incisions
title_short	In vivo and in vitro analysis of topographic changes secondary to DSAEK venting incisions
title_full	In vivo and in vitro analysis of topographic changes secondary to DSAEK venting incisions
title_fullStr	In vivo and in vitro analysis of topographic changes secondary to DSAEK venting incisions
title_full_unstemmed	In vivo and in vitro analysis of topographic changes secondary to DSAEK venting incisions
title_sort	in vivo and in vitro analysis of topographic changes secondary to dsaek venting incisions
publisher	Dove Medical Press
publishDate	2011
url	https://doaj.org/article/b2bfecd43e0a41db8555b11e0890f670
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In vivo and in vitro analysis of topographic changes secondary to DSAEK venting incisions

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