The notch ligand delta-like 4 regulates multiple stages of early hemato-vascular development.

The notch ligand delta-like 4 regulates multiple stages of early hemato-vascular development.

<h4>Background</h4>In mouse embryos, homozygous or heterozygous deletions of the gene encoding the Notch ligand Dll4 result in early embryonic death due to major defects in endothelial remodeling in the yolk sac and embryo. Considering the close developmental relationship between endothe...

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Autores principales: Ricardo Laranjeiro, Isabel Alcobia, Hélia Neves, Andreia C Gomes, Pedro Saavedra, Catarina C Carvalho, António Duarte, António Cidadão, Leonor Parreira
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/b3031ee285004764ba16000a8b3e42c2
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