A multiplexable TALE-based binary expression system for in vivo cellular interaction studies

Binary expression systems enable researchers to deliver loss-of-function or gain-of-function transgenes with spatial-temporal resolution in vivo. Here, the authors present a programmable TALE-based system for multiplexed orthogonal activation of transgenes in Drosophila.

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Autores principales:	Markus Toegel, Ghows Azzam, Eunice Y. Lee, David J. H. F. Knapp, Ying Tan, Ming Fa, Tudor A. Fulga
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b30571d62f584df9bcba980fa93d1565
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spelling	oai:doaj.org-article:b30571d62f584df9bcba980fa93d15652021-12-02T14:41:18ZA multiplexable TALE-based binary expression system for in vivo cellular interaction studies10.1038/s41467-017-01592-32041-1723https://doaj.org/article/b30571d62f584df9bcba980fa93d15652017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01592-3https://doaj.org/toc/2041-1723Binary expression systems enable researchers to deliver loss-of-function or gain-of-function transgenes with spatial-temporal resolution in vivo. Here, the authors present a programmable TALE-based system for multiplexed orthogonal activation of transgenes in Drosophila.Markus ToegelGhows AzzamEunice Y. LeeDavid J. H. F. KnappYing TanMing FaTudor A. FulgaNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Markus Toegel Ghows Azzam Eunice Y. Lee David J. H. F. Knapp Ying Tan Ming Fa Tudor A. Fulga A multiplexable TALE-based binary expression system for in vivo cellular interaction studies
description	Binary expression systems enable researchers to deliver loss-of-function or gain-of-function transgenes with spatial-temporal resolution in vivo. Here, the authors present a programmable TALE-based system for multiplexed orthogonal activation of transgenes in Drosophila.
format	article
author	Markus Toegel Ghows Azzam Eunice Y. Lee David J. H. F. Knapp Ying Tan Ming Fa Tudor A. Fulga
author_facet	Markus Toegel Ghows Azzam Eunice Y. Lee David J. H. F. Knapp Ying Tan Ming Fa Tudor A. Fulga
author_sort	Markus Toegel
title	A multiplexable TALE-based binary expression system for in vivo cellular interaction studies
title_short	A multiplexable TALE-based binary expression system for in vivo cellular interaction studies
title_full	A multiplexable TALE-based binary expression system for in vivo cellular interaction studies
title_fullStr	A multiplexable TALE-based binary expression system for in vivo cellular interaction studies
title_full_unstemmed	A multiplexable TALE-based binary expression system for in vivo cellular interaction studies
title_sort	multiplexable tale-based binary expression system for in vivo cellular interaction studies
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/b30571d62f584df9bcba980fa93d1565
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A multiplexable TALE-based binary expression system for in vivo cellular interaction studies

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