Random or stochastic monoallelic expressed genes are enriched for neurodevelopmental disorder candidate genes.

Random or stochastic monoallelic expressed genes are enriched for neurodevelopmental disorder candidate genes.

Random or stochastic monoallelic expressed genes (StMA genes) represent a unique form of monoallelic expression where allelic choice is made at random early in development. The consequential clonal diversity provides opportunity for functional heterozygosity in tissues such as the brain, and can imp...

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Autores principales: Aaron R Jeffries, David A Collier, Evangelos Vassos, Sarah Curran, Caroline M Ogilvie, Jack Price
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/b30d26637f4346c4be34bc0525abbfb6
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