Overcoming MCL-1-driven adaptive resistance to targeted therapies
Two complementary studies in Nature Communications define a critical role for the anti-apoptotic protein MCL-1 as a driver of adaptive survival in tumor cells treated with oncogene targeted therapies, providing a rationale for combining these agents with newly developed MCL-1 inhibitors in the clini...
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| Format: | article |
| Language: | EN |
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Nature Portfolio
2020
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| Subjects: | |
| Online Access: | https://doaj.org/article/b3104b61e16b45ff87d587459438569d |
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