Detection and quantification of γ-H2AX using a dissociation enhanced lanthanide fluorescence immunoassay
Abstract Phosphorylation of the histone protein H2AX to form γ-H2AX foci directly represents DNA double-strand break formation. Traditional γ-H2AX detection involves counting individual foci within individual nuclei. The novelty of this work is the application of a time-resolved fluorescence assay u...
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Autores principales: | Felicite K. Noubissi, Amber A. McBride, Hannah G. Leppert, Larry J. Millet, Xiaofei Wang, Sandra M. Davern |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/b318484cefd641de873ac56966a7f9c7 |
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