Characterization of slow cycling corneal limbal epithelial cells identifies putative stem cell markers

Characterization of slow cycling corneal limbal epithelial cells identifies putative stem cell markers

Abstract In order to identify reliable markers of corneal epithelial stem cells, we employed an inducible transgenic “pulse-chase” murine model (K5Tta × TRE-H2BGFP) to localize, purify, and characterize slow cycling cells in the cornea. The retention of GFP labeling in slowly dividing cells allowed...

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Main Authors: R. Sartaj, C. Zhang, P. Wan, Z. Pasha, V. Guaiquil, A. Liu, J. Liu, Y. Luo, E. Fuchs, M. I. Rosenblatt
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/b31cbe537ed04dd89331331bb538a1da
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