B7-H1-deficiency enhances the potential of tolerogenic dendritic cells by activating CD1d-restricted type II NKT cells.

B7-H1-deficiency enhances the potential of tolerogenic dendritic cells by activating CD1d-restricted type II NKT cells.

<h4>Background</h4>Dendritic cells (DC) can act tolerogenic at a semi-mature stage by induction of protective CD4(+) T cell and NKT cell responses.<h4>Methodology/principal findings</h4>Here we studied the role of the co-inhibitory molecule B7-H1 (PD-L1, CD274) on semi-mature...

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Autores principales: Carolin Brandl, Sonja Ortler, Thomas Herrmann, Susanna Cardell, Manfred B Lutz, Heinz Wiendl
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/b31f1ec16bec437daa228ad4988f7213
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