Aβ-induced vulnerability propagates via the brain’s default mode network

Aβ-induced vulnerability propagates via the brain’s default mode network

Amyloid-β (Aβ) deposition occurs in Alzheimer's disease but its relation to disease features such as local brain hypometabolism or cognitive decline is unclear. Here, the authors show that Aβ aggregation in the brain’s default mode network leads to hypometabolism in distant but functionally con...

Full description

Saved in:
Bibliographic Details
Main Authors: Tharick A. Pascoal, Sulantha Mathotaarachchi, Min Su Kang, Sara Mohaddes, Monica Shin, Ah Yeon Park, Maxime J. Parent, Andrea L. Benedet, Mira Chamoun, Joseph Therriault, Heungsun Hwang, A. Claudio Cuello, Bratislav Misic, Jean-Paul Soucy, John A. D. Aston, Serge Gauthier, Pedro Rosa-Neto
Format: article
Language:EN
Published: Nature Portfolio 2019
Subjects:
Science
Q
Online Access:https://doaj.org/article/b3232c605c38460fa526e6a7ba30b7cd
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/b3232c605c38460fa526e6a7ba30b7cd

Similar Items