Disordered flanks prevent peptide aggregation.
Natively unstructured or disordered regions appear to be abundant in eukaryotic proteins. Many such regions have been found alongside small linear binding motifs. We report a Monte Carlo study that aims to elucidate the role of disordered regions adjacent to such binding motifs. The coarse-grained s...
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Main Authors: | Sanne Abeln, Daan Frenkel |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2008
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Online Access: | https://doaj.org/article/b329eb55103644ce8989b2e9a27c9e01 |
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