Nanopore blockade sensors for ultrasensitive detection of proteins in complex biological samples

Nanopore sensors have long analysis times when analytes are at low concentration and non-specific signals in complex media. Here the authors use antibody-modified magnetic nanoparticles to detect prostate-specific antigen at sub-femtomolar concentrations in blood.

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Detalles Bibliográficos
Autores principales: Kyloon Chuah, Yanfang Wu, S. R. C. Vivekchand, Katharina Gaus, Peter J. Reece, Adam P. Micolich, J. Justin Gooding
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/b333959b1b6b4d21b34449c128820b97
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Descripción
Sumario:Nanopore sensors have long analysis times when analytes are at low concentration and non-specific signals in complex media. Here the authors use antibody-modified magnetic nanoparticles to detect prostate-specific antigen at sub-femtomolar concentrations in blood.