Standardized Nanomechanical Atomic Force Microscopy Procedure (SNAP) for Measuring Soft and Biological Samples

Standardized Nanomechanical Atomic Force Microscopy Procedure (SNAP) for Measuring Soft and Biological Samples

Abstract We present a procedure that allows a reliable determination of the elastic (Young’s) modulus of soft samples, including living cells, by atomic force microscopy (AFM). The standardized nanomechanical AFM procedure (SNAP) ensures the precise adjustment of the AFM optical lever system, a prer...

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Main Authors: Hermann Schillers, Carmela Rianna, Jens Schäpe, Tomas Luque, Holger Doschke, Mike Wälte, Juan José Uriarte, Noelia Campillo, Georgios P. A. Michanetzis, Justyna Bobrowska, Andra Dumitru, Elena T. Herruzo, Simone Bovio, Pierre Parot, Massimiliano Galluzzi, Alessandro Podestà, Luca Puricelli, Simon Scheuring, Yannis Missirlis, Ricardo Garcia, Michael Odorico, Jean-Marie Teulon, Frank Lafont, Malgorzata Lekka, Felix Rico, Annafrancesca Rigato, Jean-Luc Pellequer, Hans Oberleithner, Daniel Navajas, Manfred Radmacher
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/b340d2b52d6746c3a98d8f60fb8b97bf
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