Downregulation of Src-family tyrosine kinases by Srcasm and c-Cbl: A comparative analysis

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Downregulation of Src-family tyrosine kinases by Srcasm and c-Cbl: A comparative analysis

AIM: Elevated Src-Family tyrosine kinase (SFK) activity drives carcinogenesis in vivo and elevated SFK activity is found ubiquitously in human cancers. Although human squamous cell carcinomas (SCCs) demonstrate increased SFK activity, in silico analysis of SCCs demonstrates that only 0.4% of lesions...

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Bibliographic Details
Main Authors:	Vivian Lee, Thomas D Griffin, Yoko Suzuki-Horiuchi, Lily Wushanley, Yerin Kweon, Christine Marshall, Weijie Li, Elias Ayli, Adele Haimovic, Aliya Hines, John T Seykora
Format:	article
Language:	EN
Published:	Wolters Kluwer Medknow Publications 2021
Subjects:	cancer cbl srcasm src-family kinases Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Online Access:	https://doaj.org/article/b34910f78a404e85b88aefde8e2d87af
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