Identification of the cross-strand chimeric RNAs generated by fusions of bi-directional transcripts

Gene fusion, trans-splicing or transcription read-through contributes to generation of chimeric RNA. Here the authors develop a pipeline to identify non-canonical type of chimeric RNAs called cross-strand chimeric RNA (cscRNA), which are fused between two precursor RNAs transcribed from the opposite...

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Autores principales: Yuting Wang, Qin Zou, Fajin Li, Wenwei Zhao, Hui Xu, Wenhao Zhang, Haiteng Deng, Xuerui Yang
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/b34a95e3375e4146a8fc28a8bf1d6036
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spelling oai:doaj.org-article:b34a95e3375e4146a8fc28a8bf1d60362021-12-02T16:25:00ZIdentification of the cross-strand chimeric RNAs generated by fusions of bi-directional transcripts10.1038/s41467-021-24910-22041-1723https://doaj.org/article/b34a95e3375e4146a8fc28a8bf1d60362021-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24910-2https://doaj.org/toc/2041-1723Gene fusion, trans-splicing or transcription read-through contributes to generation of chimeric RNA. Here the authors develop a pipeline to identify non-canonical type of chimeric RNAs called cross-strand chimeric RNA (cscRNA), which are fused between two precursor RNAs transcribed from the opposite DNA strands.Yuting WangQin ZouFajin LiWenwei ZhaoHui XuWenhao ZhangHaiteng DengXuerui YangNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yuting Wang
Qin Zou
Fajin Li
Wenwei Zhao
Hui Xu
Wenhao Zhang
Haiteng Deng
Xuerui Yang
Identification of the cross-strand chimeric RNAs generated by fusions of bi-directional transcripts
description Gene fusion, trans-splicing or transcription read-through contributes to generation of chimeric RNA. Here the authors develop a pipeline to identify non-canonical type of chimeric RNAs called cross-strand chimeric RNA (cscRNA), which are fused between two precursor RNAs transcribed from the opposite DNA strands.
format article
author Yuting Wang
Qin Zou
Fajin Li
Wenwei Zhao
Hui Xu
Wenhao Zhang
Haiteng Deng
Xuerui Yang
author_facet Yuting Wang
Qin Zou
Fajin Li
Wenwei Zhao
Hui Xu
Wenhao Zhang
Haiteng Deng
Xuerui Yang
author_sort Yuting Wang
title Identification of the cross-strand chimeric RNAs generated by fusions of bi-directional transcripts
title_short Identification of the cross-strand chimeric RNAs generated by fusions of bi-directional transcripts
title_full Identification of the cross-strand chimeric RNAs generated by fusions of bi-directional transcripts
title_fullStr Identification of the cross-strand chimeric RNAs generated by fusions of bi-directional transcripts
title_full_unstemmed Identification of the cross-strand chimeric RNAs generated by fusions of bi-directional transcripts
title_sort identification of the cross-strand chimeric rnas generated by fusions of bi-directional transcripts
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/b34a95e3375e4146a8fc28a8bf1d6036
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AT fajinli identificationofthecrossstrandchimericrnasgeneratedbyfusionsofbidirectionaltranscripts
AT wenweizhao identificationofthecrossstrandchimericrnasgeneratedbyfusionsofbidirectionaltranscripts
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