Comparison of the results of clinical and morphological methods of research in HPV-associated diseases of the cervix (retrospective study)

Aim. To conduct a retrospective analysis and evaluate the morphological methods for HPV-related intraepithelial lesions detection in women of reproductive age. Materials and methods. The data of cytological diagnosis, as well as the results of histological reports were analyzed for the period fro...

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Autores principales:	Djamilya I. Attoeva, Alexandra V. Asaturova, Vera N. Prilepskaya, Nataliia L. Starodubtseva, Polina L. Sheshko, Ada T. Uruymagova
Formato:	article
Lenguaje:	RU
Publicado:	IP Berlin A.V. 2021
Materias:	cervical intraepithelial lesions nilm asc-us lsil hsil cytological examination histological diagnosis cytology-histology correlation Gynecology and obstetrics RG1-991
Acceso en línea:	https://doaj.org/article/b34c5f8c327d47a39b4ffff7b11ca55c
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spelling	oai:doaj.org-article:b34c5f8c327d47a39b4ffff7b11ca55c2021-12-02T19:22:24ZComparison of the results of clinical and morphological methods of research in HPV-associated diseases of the cervix (retrospective study)2079-56962079-583110.26442/20795696.2021.1.200647https://doaj.org/article/b34c5f8c327d47a39b4ffff7b11ca55c2021-03-01T00:00:00Zhttps://gynecology.orscience.ru/2079-5831/article/viewFile/63739/46703https://doaj.org/toc/2079-5696https://doaj.org/toc/2079-5831Aim. To conduct a retrospective analysis and evaluate the morphological methods for HPV-related intraepithelial lesions detection in women of reproductive age. Materials and methods. The data of cytological diagnosis, as well as the results of histological reports were analyzed for the period from 2018 to 2019. A comparative analysis was performed in 415 patients with HPV-related intraepithelial lesions, who applied to the scientific and polyclinic department of the Kulakov National Research Medical Center at the age of 19 to 45 years. Morphological examination was carried out by specialists of the 1st pathology department of the Center. Results. According to the results of a comparative analysis of cytological and histological conclusions, 3 groups were formed: 1 the group of coincidence (agree) of cytological and histological conclusions; 2 group of minor discrepancies (minor under/ over) between cytological and histological finding; 3 group of major discrepancies (major under/ over) between cytological and histological findings. Cytological and histological compliance was achieved in 194 (46.74%) patients. The total number of minor nonconformities was 192 (46%) cases. The total number of significant discrepancies between cytological and histological findings was 29 (6.9%) patients: 20 (4.8%) cases were found in the group NILM, hr. cervicitis HSIL and 9 (2.1%) cases in the group HSIL hr. cervicitis according to the results of histological examination. Conclusion. Cervical screening reduces the risk of breast cancer due to cytological examination of the cervix, but histological examination is crucial in making a correct diagnosis, since its result determines the choice of treatment method. The comparative analysis showed that in all groups there were cases of hypo- and hyperdiagnostics during cytological examination although the major discrepancies which can change treatment algorithm, were found only in 6.8% cases.Djamilya I. AttoevaAlexandra V. AsaturovaVera N. PrilepskayaNataliia L. StarodubtsevaPolina L. SheshkoAda T. UruymagovaIP Berlin A.V. articlecervical intraepithelial lesionsnilmasc-uslsilhsilcytological examinationhistological diagnosiscytology-histology correlationGynecology and obstetricsRG1-991RUГинекология, Vol 23, Iss 1, Pp 78-82 (2021)
institution	DOAJ
collection	DOAJ
language	RU
topic	cervical intraepithelial lesions nilm asc-us lsil hsil cytological examination histological diagnosis cytology-histology correlation Gynecology and obstetrics RG1-991
spellingShingle	cervical intraepithelial lesions nilm asc-us lsil hsil cytological examination histological diagnosis cytology-histology correlation Gynecology and obstetrics RG1-991 Djamilya I. Attoeva Alexandra V. Asaturova Vera N. Prilepskaya Nataliia L. Starodubtseva Polina L. Sheshko Ada T. Uruymagova Comparison of the results of clinical and morphological methods of research in HPV-associated diseases of the cervix (retrospective study)
description	Aim. To conduct a retrospective analysis and evaluate the morphological methods for HPV-related intraepithelial lesions detection in women of reproductive age. Materials and methods. The data of cytological diagnosis, as well as the results of histological reports were analyzed for the period from 2018 to 2019. A comparative analysis was performed in 415 patients with HPV-related intraepithelial lesions, who applied to the scientific and polyclinic department of the Kulakov National Research Medical Center at the age of 19 to 45 years. Morphological examination was carried out by specialists of the 1st pathology department of the Center. Results. According to the results of a comparative analysis of cytological and histological conclusions, 3 groups were formed: 1 the group of coincidence (agree) of cytological and histological conclusions; 2 group of minor discrepancies (minor under/ over) between cytological and histological finding; 3 group of major discrepancies (major under/ over) between cytological and histological findings. Cytological and histological compliance was achieved in 194 (46.74%) patients. The total number of minor nonconformities was 192 (46%) cases. The total number of significant discrepancies between cytological and histological findings was 29 (6.9%) patients: 20 (4.8%) cases were found in the group NILM, hr. cervicitis HSIL and 9 (2.1%) cases in the group HSIL hr. cervicitis according to the results of histological examination. Conclusion. Cervical screening reduces the risk of breast cancer due to cytological examination of the cervix, but histological examination is crucial in making a correct diagnosis, since its result determines the choice of treatment method. The comparative analysis showed that in all groups there were cases of hypo- and hyperdiagnostics during cytological examination although the major discrepancies which can change treatment algorithm, were found only in 6.8% cases.
format	article
author	Djamilya I. Attoeva Alexandra V. Asaturova Vera N. Prilepskaya Nataliia L. Starodubtseva Polina L. Sheshko Ada T. Uruymagova
author_facet	Djamilya I. Attoeva Alexandra V. Asaturova Vera N. Prilepskaya Nataliia L. Starodubtseva Polina L. Sheshko Ada T. Uruymagova
author_sort	Djamilya I. Attoeva
title	Comparison of the results of clinical and morphological methods of research in HPV-associated diseases of the cervix (retrospective study)
title_short	Comparison of the results of clinical and morphological methods of research in HPV-associated diseases of the cervix (retrospective study)
title_full	Comparison of the results of clinical and morphological methods of research in HPV-associated diseases of the cervix (retrospective study)
title_fullStr	Comparison of the results of clinical and morphological methods of research in HPV-associated diseases of the cervix (retrospective study)
title_full_unstemmed	Comparison of the results of clinical and morphological methods of research in HPV-associated diseases of the cervix (retrospective study)
title_sort	comparison of the results of clinical and morphological methods of research in hpv-associated diseases of the cervix (retrospective study)
publisher	IP Berlin A.V.
publishDate	2021
url	https://doaj.org/article/b34c5f8c327d47a39b4ffff7b11ca55c
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Comparison of the results of clinical and morphological methods of research in HPV-associated diseases of the cervix (retrospective study)

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