Tailing and degradation of Argonaute-bound small RNAs protect the genome from uncontrolled RNAi

While RNA interference is a highly conserved mechanism of gene regulation, how Argonaute-bound small RNAs are targeted for degradation is not well understood. Here the authors show that Cid14 and Cid16 target Argonaute-bound small RNAs for degradation and protect the genome from uncontrolled RNAi ac...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Paola Pisacane, Mario Halic
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b354a2a9d2b54d4498ba1ed17e081328
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:b354a2a9d2b54d4498ba1ed17e081328
record_format	dspace
spelling	oai:doaj.org-article:b354a2a9d2b54d4498ba1ed17e0813282021-12-02T14:40:26ZTailing and degradation of Argonaute-bound small RNAs protect the genome from uncontrolled RNAi10.1038/ncomms153322041-1723https://doaj.org/article/b354a2a9d2b54d4498ba1ed17e0813282017-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms15332https://doaj.org/toc/2041-1723While RNA interference is a highly conserved mechanism of gene regulation, how Argonaute-bound small RNAs are targeted for degradation is not well understood. Here the authors show that Cid14 and Cid16 target Argonaute-bound small RNAs for degradation and protect the genome from uncontrolled RNAi activity.Paola PisacaneMario HalicNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Paola Pisacane Mario Halic Tailing and degradation of Argonaute-bound small RNAs protect the genome from uncontrolled RNAi
description	While RNA interference is a highly conserved mechanism of gene regulation, how Argonaute-bound small RNAs are targeted for degradation is not well understood. Here the authors show that Cid14 and Cid16 target Argonaute-bound small RNAs for degradation and protect the genome from uncontrolled RNAi activity.
format	article
author	Paola Pisacane Mario Halic
author_facet	Paola Pisacane Mario Halic
author_sort	Paola Pisacane
title	Tailing and degradation of Argonaute-bound small RNAs protect the genome from uncontrolled RNAi
title_short	Tailing and degradation of Argonaute-bound small RNAs protect the genome from uncontrolled RNAi
title_full	Tailing and degradation of Argonaute-bound small RNAs protect the genome from uncontrolled RNAi
title_fullStr	Tailing and degradation of Argonaute-bound small RNAs protect the genome from uncontrolled RNAi
title_full_unstemmed	Tailing and degradation of Argonaute-bound small RNAs protect the genome from uncontrolled RNAi
title_sort	tailing and degradation of argonaute-bound small rnas protect the genome from uncontrolled rnai
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/b354a2a9d2b54d4498ba1ed17e081328
work_keys_str_mv	AT paolapisacane tailinganddegradationofargonauteboundsmallrnasprotectthegenomefromuncontrolledrnai AT mariohalic tailinganddegradationofargonauteboundsmallrnasprotectthegenomefromuncontrolledrnai
_version_	1718390318978564096

Tailing and degradation of Argonaute-bound small RNAs protect the genome from uncontrolled RNAi

Ejemplares similares