Plant-Based, Antioxidant-Rich Snacks Elevate Plasma Antioxidant Ability and Alter Gut Bacterial Composition in Older Adults

Plant-rich diets alleviate oxidative stress and gut dysbiosis and are negatively linked to age-associated chronic disorders. This study examined the effects of consuming plant-based, antioxidant-rich smoothies and sesame seed snacks (PBASS) on antioxidant ability and gut microbial composition in old...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Jing-Yao Zhang, Hui-Chen Lo, Feili Lo Yang, Yi-Fang Liu, Wen-Mein Wu, Chi-Chun Chou
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	antioxidant enzymes gut microbiota older adults plant foods total antioxidant capacity Nutrition. Foods and food supply TX341-641
Acceso en línea:	https://doaj.org/article/b35509c8380945a0a21c15bf728e615c
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:b35509c8380945a0a21c15bf728e615c
record_format	dspace
spelling	oai:doaj.org-article:b35509c8380945a0a21c15bf728e615c2021-11-25T18:34:49ZPlant-Based, Antioxidant-Rich Snacks Elevate Plasma Antioxidant Ability and Alter Gut Bacterial Composition in Older Adults10.3390/nu131138722072-6643https://doaj.org/article/b35509c8380945a0a21c15bf728e615c2021-10-01T00:00:00Zhttps://www.mdpi.com/2072-6643/13/11/3872https://doaj.org/toc/2072-6643Plant-rich diets alleviate oxidative stress and gut dysbiosis and are negatively linked to age-associated chronic disorders. This study examined the effects of consuming plant-based, antioxidant-rich smoothies and sesame seed snacks (PBASS) on antioxidant ability and gut microbial composition in older adults. Healthy and sub-healthy older adults (<i>n</i> = 42, 79.7 ± 8.6 years old) in two senior living facilities were given PBASS for 4 months. Blood and fecal samples were collected from these individuals at the baseline and after 2 and 4 months of PBASS consumption. After 2 months, serum levels of albumin and high-density lipoprotein-cholesterol and the ratio of reduced to oxidized glutathione (GSH/GSSG) had increased significantly and erythrocytic glutathione, GSH/GSSG and superoxide dismutase activity had decreased significantly compared with baseline levels (<i>p</i> < 0.05). After 4 months, red blood cells, hematocrit, serum blood urea nitrogen and erythrocyte glutathione peroxidase activity had decreased significantly, whereas plasma and erythrocyte protein-bound sulfhydryl groups had increased significantly. Furthermore, plasma glutathione and total antioxidant capacity were significantly greater after 2 months and increased further after 4 months of PBASS consumption. The results of next generation sequencing showed that PBASS consumption prompted significant decreases in observed bacterial species, their richness, and the abundance of Actinobacteria and Patescibacteria and increases in Bacteroidetes in feces. Our results suggest that texture-modified, plant-based snacks are useful nutrition support to benefit healthy ageing via the elevation of antioxidant ability and alteration of gut microbiota.Jing-Yao ZhangHui-Chen LoFeili Lo YangYi-Fang LiuWen-Mein WuChi-Chun ChouMDPI AGarticleantioxidant enzymesgut microbiotaolder adultsplant foodstotal antioxidant capacityNutrition. Foods and food supplyTX341-641ENNutrients, Vol 13, Iss 3872, p 3872 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	antioxidant enzymes gut microbiota older adults plant foods total antioxidant capacity Nutrition. Foods and food supply TX341-641
spellingShingle	antioxidant enzymes gut microbiota older adults plant foods total antioxidant capacity Nutrition. Foods and food supply TX341-641 Jing-Yao Zhang Hui-Chen Lo Feili Lo Yang Yi-Fang Liu Wen-Mein Wu Chi-Chun Chou Plant-Based, Antioxidant-Rich Snacks Elevate Plasma Antioxidant Ability and Alter Gut Bacterial Composition in Older Adults
description	Plant-rich diets alleviate oxidative stress and gut dysbiosis and are negatively linked to age-associated chronic disorders. This study examined the effects of consuming plant-based, antioxidant-rich smoothies and sesame seed snacks (PBASS) on antioxidant ability and gut microbial composition in older adults. Healthy and sub-healthy older adults (<i>n</i> = 42, 79.7 ± 8.6 years old) in two senior living facilities were given PBASS for 4 months. Blood and fecal samples were collected from these individuals at the baseline and after 2 and 4 months of PBASS consumption. After 2 months, serum levels of albumin and high-density lipoprotein-cholesterol and the ratio of reduced to oxidized glutathione (GSH/GSSG) had increased significantly and erythrocytic glutathione, GSH/GSSG and superoxide dismutase activity had decreased significantly compared with baseline levels (<i>p</i> < 0.05). After 4 months, red blood cells, hematocrit, serum blood urea nitrogen and erythrocyte glutathione peroxidase activity had decreased significantly, whereas plasma and erythrocyte protein-bound sulfhydryl groups had increased significantly. Furthermore, plasma glutathione and total antioxidant capacity were significantly greater after 2 months and increased further after 4 months of PBASS consumption. The results of next generation sequencing showed that PBASS consumption prompted significant decreases in observed bacterial species, their richness, and the abundance of Actinobacteria and Patescibacteria and increases in Bacteroidetes in feces. Our results suggest that texture-modified, plant-based snacks are useful nutrition support to benefit healthy ageing via the elevation of antioxidant ability and alteration of gut microbiota.
format	article
author	Jing-Yao Zhang Hui-Chen Lo Feili Lo Yang Yi-Fang Liu Wen-Mein Wu Chi-Chun Chou
author_facet	Jing-Yao Zhang Hui-Chen Lo Feili Lo Yang Yi-Fang Liu Wen-Mein Wu Chi-Chun Chou
author_sort	Jing-Yao Zhang
title	Plant-Based, Antioxidant-Rich Snacks Elevate Plasma Antioxidant Ability and Alter Gut Bacterial Composition in Older Adults
title_short	Plant-Based, Antioxidant-Rich Snacks Elevate Plasma Antioxidant Ability and Alter Gut Bacterial Composition in Older Adults
title_full	Plant-Based, Antioxidant-Rich Snacks Elevate Plasma Antioxidant Ability and Alter Gut Bacterial Composition in Older Adults
title_fullStr	Plant-Based, Antioxidant-Rich Snacks Elevate Plasma Antioxidant Ability and Alter Gut Bacterial Composition in Older Adults
title_full_unstemmed	Plant-Based, Antioxidant-Rich Snacks Elevate Plasma Antioxidant Ability and Alter Gut Bacterial Composition in Older Adults
title_sort	plant-based, antioxidant-rich snacks elevate plasma antioxidant ability and alter gut bacterial composition in older adults
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/b35509c8380945a0a21c15bf728e615c
work_keys_str_mv	AT jingyaozhang plantbasedantioxidantrichsnackselevateplasmaantioxidantabilityandaltergutbacterialcompositioninolderadults AT huichenlo plantbasedantioxidantrichsnackselevateplasmaantioxidantabilityandaltergutbacterialcompositioninolderadults AT feililoyang plantbasedantioxidantrichsnackselevateplasmaantioxidantabilityandaltergutbacterialcompositioninolderadults AT yifangliu plantbasedantioxidantrichsnackselevateplasmaantioxidantabilityandaltergutbacterialcompositioninolderadults AT wenmeinwu plantbasedantioxidantrichsnackselevateplasmaantioxidantabilityandaltergutbacterialcompositioninolderadults AT chichunchou plantbasedantioxidantrichsnackselevateplasmaantioxidantabilityandaltergutbacterialcompositioninolderadults
_version_	1718410972464414720

Plant-Based, Antioxidant-Rich Snacks Elevate Plasma Antioxidant Ability and Alter Gut Bacterial Composition in Older Adults

Ejemplares similares