Synthesizing AND gate minigene circuits based on CRISPReader for identification of bladder cancer cells

Synthetic biology logic gates can be used to distinguish healthy cells from cancer cells. Here the authors design minigene circuits that show more robust identification of cancer cells compared to traditional genetic circuits.

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Detalles Bibliográficos
Autores principales: Yuchen Liu, Weiren Huang, Zhiming Cai
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/b35a492ebfc2448f84ba03589e53de3a
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Sumario:Synthetic biology logic gates can be used to distinguish healthy cells from cancer cells. Here the authors design minigene circuits that show more robust identification of cancer cells compared to traditional genetic circuits.