Synthesizing AND gate minigene circuits based on CRISPReader for identification of bladder cancer cells
Synthetic biology logic gates can be used to distinguish healthy cells from cancer cells. Here the authors design minigene circuits that show more robust identification of cancer cells compared to traditional genetic circuits.
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Nature Portfolio
2020
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oai:doaj.org-article:b35a492ebfc2448f84ba03589e53de3a2021-12-02T17:32:41ZSynthesizing AND gate minigene circuits based on CRISPReader for identification of bladder cancer cells10.1038/s41467-020-19314-72041-1723https://doaj.org/article/b35a492ebfc2448f84ba03589e53de3a2020-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19314-7https://doaj.org/toc/2041-1723Synthetic biology logic gates can be used to distinguish healthy cells from cancer cells. Here the authors design minigene circuits that show more robust identification of cancer cells compared to traditional genetic circuits.Yuchen LiuWeiren HuangZhiming CaiNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-9 (2020) |
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Science Q Yuchen Liu Weiren Huang Zhiming Cai Synthesizing AND gate minigene circuits based on CRISPReader for identification of bladder cancer cells |
description |
Synthetic biology logic gates can be used to distinguish healthy cells from cancer cells. Here the authors design minigene circuits that show more robust identification of cancer cells compared to traditional genetic circuits. |
format |
article |
author |
Yuchen Liu Weiren Huang Zhiming Cai |
author_facet |
Yuchen Liu Weiren Huang Zhiming Cai |
author_sort |
Yuchen Liu |
title |
Synthesizing AND gate minigene circuits based on CRISPReader for identification of bladder cancer cells |
title_short |
Synthesizing AND gate minigene circuits based on CRISPReader for identification of bladder cancer cells |
title_full |
Synthesizing AND gate minigene circuits based on CRISPReader for identification of bladder cancer cells |
title_fullStr |
Synthesizing AND gate minigene circuits based on CRISPReader for identification of bladder cancer cells |
title_full_unstemmed |
Synthesizing AND gate minigene circuits based on CRISPReader for identification of bladder cancer cells |
title_sort |
synthesizing and gate minigene circuits based on crispreader for identification of bladder cancer cells |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/b35a492ebfc2448f84ba03589e53de3a |
work_keys_str_mv |
AT yuchenliu synthesizingandgateminigenecircuitsbasedoncrispreaderforidentificationofbladdercancercells AT weirenhuang synthesizingandgateminigenecircuitsbasedoncrispreaderforidentificationofbladdercancercells AT zhimingcai synthesizingandgateminigenecircuitsbasedoncrispreaderforidentificationofbladdercancercells |
_version_ |
1718380209013522432 |