Synthesizing AND gate minigene circuits based on CRISPReader for identification of bladder cancer cells

Synthetic biology logic gates can be used to distinguish healthy cells from cancer cells. Here the authors design minigene circuits that show more robust identification of cancer cells compared to traditional genetic circuits.

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Autores principales: Yuchen Liu, Weiren Huang, Zhiming Cai
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/b35a492ebfc2448f84ba03589e53de3a
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spelling oai:doaj.org-article:b35a492ebfc2448f84ba03589e53de3a2021-12-02T17:32:41ZSynthesizing AND gate minigene circuits based on CRISPReader for identification of bladder cancer cells10.1038/s41467-020-19314-72041-1723https://doaj.org/article/b35a492ebfc2448f84ba03589e53de3a2020-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19314-7https://doaj.org/toc/2041-1723Synthetic biology logic gates can be used to distinguish healthy cells from cancer cells. Here the authors design minigene circuits that show more robust identification of cancer cells compared to traditional genetic circuits.Yuchen LiuWeiren HuangZhiming CaiNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yuchen Liu
Weiren Huang
Zhiming Cai
Synthesizing AND gate minigene circuits based on CRISPReader for identification of bladder cancer cells
description Synthetic biology logic gates can be used to distinguish healthy cells from cancer cells. Here the authors design minigene circuits that show more robust identification of cancer cells compared to traditional genetic circuits.
format article
author Yuchen Liu
Weiren Huang
Zhiming Cai
author_facet Yuchen Liu
Weiren Huang
Zhiming Cai
author_sort Yuchen Liu
title Synthesizing AND gate minigene circuits based on CRISPReader for identification of bladder cancer cells
title_short Synthesizing AND gate minigene circuits based on CRISPReader for identification of bladder cancer cells
title_full Synthesizing AND gate minigene circuits based on CRISPReader for identification of bladder cancer cells
title_fullStr Synthesizing AND gate minigene circuits based on CRISPReader for identification of bladder cancer cells
title_full_unstemmed Synthesizing AND gate minigene circuits based on CRISPReader for identification of bladder cancer cells
title_sort synthesizing and gate minigene circuits based on crispreader for identification of bladder cancer cells
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/b35a492ebfc2448f84ba03589e53de3a
work_keys_str_mv AT yuchenliu synthesizingandgateminigenecircuitsbasedoncrispreaderforidentificationofbladdercancercells
AT weirenhuang synthesizingandgateminigenecircuitsbasedoncrispreaderforidentificationofbladdercancercells
AT zhimingcai synthesizingandgateminigenecircuitsbasedoncrispreaderforidentificationofbladdercancercells
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