NEONATAL SEPSIS IN A TERTIARY CARE HOSPITAL: BACTERIOLOGICAL PROFILE AND ITS ANTIBICROBIAL SENSITIVITY

Objective: To study the spectrum and antimicrobial sensitivity of bacterial pathogens causing neonatal sepsis, in neonatal intensive care unit (NICU) of Pak Emirates Military Hospital, Rawalpindi. Study Design: Prospective cross sectional study. Place and Duration of Study: This was a prosp...

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Autores principales:	Madiha Ahmed, Muhammad Yasrab, Arshad Khushdil, Khadija Qamar, Zeeshan Ahmed
Formato:	article
Lenguaje:	EN
Publicado:	Army Medical College Rawalpindi 2018
Materias:	antimicrobial sensitivity bacteriological profile multi drug resistance Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/b35afaf8c2874f42be75c7091f5a4adb
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spelling	oai:doaj.org-article:b35afaf8c2874f42be75c7091f5a4adb2021-11-26T03:34:48ZNEONATAL SEPSIS IN A TERTIARY CARE HOSPITAL: BACTERIOLOGICAL PROFILE AND ITS ANTIBICROBIAL SENSITIVITY0030-96482411-8842https://doaj.org/article/b35afaf8c2874f42be75c7091f5a4adb2018-12-01T00:00:00Zhttps://www.pafmj.org/index.php/PAFMJ/article/view/2566/2103https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To study the spectrum and antimicrobial sensitivity of bacterial pathogens causing neonatal sepsis, in neonatal intensive care unit (NICU) of Pak Emirates Military Hospital, Rawalpindi. Study Design: Prospective cross sectional study. Place and Duration of Study: This was a prospective cross sectional study, conducted at NICU of Military Hospital, Rawalpindi, from Jul 2017 to Dec 2017. Material and Methods: All neonates admitted to our department who underwent evaluation for sepsis, from Jul 2017 to Dec 2017. Results: Out of 2,480 admitted neonates, 733 were suspected with sepsis, making an incidence of suspected neonatal sepsis to be 29.5%. 421 (57.4%) babies were suspected with early onset sepsis (EOS) and 312 (42.6%) with late onset sepsis (LOS). Majority of the babies (70.3%) were preterm. In 281 (11.3%) neonates, blood culture came out to be positive. 73/281 neonates with culture proven sepsis died making a mortality rate of 25.9%. Gram negative bacilli were most predominant among isolated bacteria. Most of the organisms showed resistance to the first line antibiotics. Conclusion: Sepsis has a high mortality rate in neonates admitted to our department. Gram negative organisms are the most common cause. Most of the isolated organisms are resistant to empirical antibiotics.Madiha AhmedMuhammad YasrabArshad KhushdilKhadija QamarZeeshan AhmedArmy Medical College Rawalpindiarticleantimicrobial sensitivitybacteriological profilemulti drug resistanceMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 68, Iss 6, Pp 1654-1658 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	antimicrobial sensitivity bacteriological profile multi drug resistance Medicine R Medicine (General) R5-920
spellingShingle	antimicrobial sensitivity bacteriological profile multi drug resistance Medicine R Medicine (General) R5-920 Madiha Ahmed Muhammad Yasrab Arshad Khushdil Khadija Qamar Zeeshan Ahmed NEONATAL SEPSIS IN A TERTIARY CARE HOSPITAL: BACTERIOLOGICAL PROFILE AND ITS ANTIBICROBIAL SENSITIVITY
description	Objective: To study the spectrum and antimicrobial sensitivity of bacterial pathogens causing neonatal sepsis, in neonatal intensive care unit (NICU) of Pak Emirates Military Hospital, Rawalpindi. Study Design: Prospective cross sectional study. Place and Duration of Study: This was a prospective cross sectional study, conducted at NICU of Military Hospital, Rawalpindi, from Jul 2017 to Dec 2017. Material and Methods: All neonates admitted to our department who underwent evaluation for sepsis, from Jul 2017 to Dec 2017. Results: Out of 2,480 admitted neonates, 733 were suspected with sepsis, making an incidence of suspected neonatal sepsis to be 29.5%. 421 (57.4%) babies were suspected with early onset sepsis (EOS) and 312 (42.6%) with late onset sepsis (LOS). Majority of the babies (70.3%) were preterm. In 281 (11.3%) neonates, blood culture came out to be positive. 73/281 neonates with culture proven sepsis died making a mortality rate of 25.9%. Gram negative bacilli were most predominant among isolated bacteria. Most of the organisms showed resistance to the first line antibiotics. Conclusion: Sepsis has a high mortality rate in neonates admitted to our department. Gram negative organisms are the most common cause. Most of the isolated organisms are resistant to empirical antibiotics.
format	article
author	Madiha Ahmed Muhammad Yasrab Arshad Khushdil Khadija Qamar Zeeshan Ahmed
author_facet	Madiha Ahmed Muhammad Yasrab Arshad Khushdil Khadija Qamar Zeeshan Ahmed
author_sort	Madiha Ahmed
title	NEONATAL SEPSIS IN A TERTIARY CARE HOSPITAL: BACTERIOLOGICAL PROFILE AND ITS ANTIBICROBIAL SENSITIVITY
title_short	NEONATAL SEPSIS IN A TERTIARY CARE HOSPITAL: BACTERIOLOGICAL PROFILE AND ITS ANTIBICROBIAL SENSITIVITY
title_full	NEONATAL SEPSIS IN A TERTIARY CARE HOSPITAL: BACTERIOLOGICAL PROFILE AND ITS ANTIBICROBIAL SENSITIVITY
title_fullStr	NEONATAL SEPSIS IN A TERTIARY CARE HOSPITAL: BACTERIOLOGICAL PROFILE AND ITS ANTIBICROBIAL SENSITIVITY
title_full_unstemmed	NEONATAL SEPSIS IN A TERTIARY CARE HOSPITAL: BACTERIOLOGICAL PROFILE AND ITS ANTIBICROBIAL SENSITIVITY
title_sort	neonatal sepsis in a tertiary care hospital: bacteriological profile and its antibicrobial sensitivity
publisher	Army Medical College Rawalpindi
publishDate	2018
url	https://doaj.org/article/b35afaf8c2874f42be75c7091f5a4adb
work_keys_str_mv	AT madihaahmed neonatalsepsisinatertiarycarehospitalbacteriologicalprofileanditsantibicrobialsensitivity AT muhammadyasrab neonatalsepsisinatertiarycarehospitalbacteriologicalprofileanditsantibicrobialsensitivity AT arshadkhushdil neonatalsepsisinatertiarycarehospitalbacteriologicalprofileanditsantibicrobialsensitivity AT khadijaqamar neonatalsepsisinatertiarycarehospitalbacteriologicalprofileanditsantibicrobialsensitivity AT zeeshanahmed neonatalsepsisinatertiarycarehospitalbacteriologicalprofileanditsantibicrobialsensitivity
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NEONATAL SEPSIS IN A TERTIARY CARE HOSPITAL: BACTERIOLOGICAL PROFILE AND ITS ANTIBICROBIAL SENSITIVITY

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