SARS-CoV-2 immunity and an overview of the COVID-19 vaccines

The remarkable development of a large number of vaccines against COVID-19 in a very short period of time represents one of the greatest successes of medicine and science in history, and mass vaccination at the global level will be crucial for prevention and mitigation of COVID-19. However, there are...

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Autor principal:	Marković Miloš
Formato:	article
Lenguaje:	EN SR
Publicado:	University of Belgrade, Medical Faculty 2021
Materias:	covid-19 sars-cov-2 variants immune response immunity vaccines booster efficiency effectiveness safety Medicine R
Acceso en línea:	https://doaj.org/article/b3652d80e8674148a6a8aa858f2e17e1
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spelling	oai:doaj.org-article:b3652d80e8674148a6a8aa858f2e17e12021-12-05T21:26:50ZSARS-CoV-2 immunity and an overview of the COVID-19 vaccines0369-15272466-552510.5937/mp72-33315https://doaj.org/article/b3652d80e8674148a6a8aa858f2e17e12021-01-01T00:00:00Zhttps://scindeks-clanci.ceon.rs/data/pdf/0369-1527/2021/0369-15272103020M.pdfhttps://doaj.org/toc/0369-1527https://doaj.org/toc/2466-5525The remarkable development of a large number of vaccines against COVID-19 in a very short period of time represents one of the greatest successes of medicine and science in history, and mass vaccination at the global level will be crucial for prevention and mitigation of COVID-19. However, there are still numerous open questions about the vaccines, and the protection they provide, and answers to those questions will not only help to control this pandemic, but they will also prepare us to react better in case of future outbreaks. This review will present the latest findings on the immune response to SARS-CoV-2 and give an update on COVID-19 immunity. It will also provide an overview of the most important vaccines against COVID-19, especially those available in Serbia, with an emphasis on their immunogenicity, efficacy and safety, as well as the platforms used for their development. In addition, a special attention will be given to open issues related to immunization against COVID-19, such as the duration of post-vaccination immunity, the degree of protection against new virus variants and the need for booster doses and mixing and matching of different COVID-19 vaccines.Marković MilošUniversity of Belgrade, Medical Facultyarticlecovid-19sars-cov-2variantsimmune responseimmunityvaccinesboosterefficiencyeffectivenesssafetyMedicineRENSRMedicinski Podmladak, Vol 72, Iss 3, Pp 20-29 (2021)
institution	DOAJ
collection	DOAJ
language	EN SR
topic	covid-19 sars-cov-2 variants immune response immunity vaccines booster efficiency effectiveness safety Medicine R
spellingShingle	covid-19 sars-cov-2 variants immune response immunity vaccines booster efficiency effectiveness safety Medicine R Marković Miloš SARS-CoV-2 immunity and an overview of the COVID-19 vaccines
description	The remarkable development of a large number of vaccines against COVID-19 in a very short period of time represents one of the greatest successes of medicine and science in history, and mass vaccination at the global level will be crucial for prevention and mitigation of COVID-19. However, there are still numerous open questions about the vaccines, and the protection they provide, and answers to those questions will not only help to control this pandemic, but they will also prepare us to react better in case of future outbreaks. This review will present the latest findings on the immune response to SARS-CoV-2 and give an update on COVID-19 immunity. It will also provide an overview of the most important vaccines against COVID-19, especially those available in Serbia, with an emphasis on their immunogenicity, efficacy and safety, as well as the platforms used for their development. In addition, a special attention will be given to open issues related to immunization against COVID-19, such as the duration of post-vaccination immunity, the degree of protection against new virus variants and the need for booster doses and mixing and matching of different COVID-19 vaccines.
format	article
author	Marković Miloš
author_facet	Marković Miloš
author_sort	Marković Miloš
title	SARS-CoV-2 immunity and an overview of the COVID-19 vaccines
title_short	SARS-CoV-2 immunity and an overview of the COVID-19 vaccines
title_full	SARS-CoV-2 immunity and an overview of the COVID-19 vaccines
title_fullStr	SARS-CoV-2 immunity and an overview of the COVID-19 vaccines
title_full_unstemmed	SARS-CoV-2 immunity and an overview of the COVID-19 vaccines
title_sort	sars-cov-2 immunity and an overview of the covid-19 vaccines
publisher	University of Belgrade, Medical Faculty
publishDate	2021
url	https://doaj.org/article/b3652d80e8674148a6a8aa858f2e17e1
work_keys_str_mv	AT markovicmilos sarscov2immunityandanoverviewofthecovid19vaccines
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SARS-CoV-2 immunity and an overview of the COVID-19 vaccines

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