Short-lived metal-centered excited state initiates iron-methionine photodissociation in ferrous cytochrome c

The dissociation mechanism of the heme axial ligand in heme proteins is not yet fully understood. The authors investigate the photodissociation dynamics of the bond between heme Fe and methionine S in ferrous cytochrome c using femtosecond time-resolved X-ray solution scattering and X-ray emission s...

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Autores principales:	Marco E. Reinhard, Michael W. Mara, Thomas Kroll, Hyeongtaek Lim, Ryan G. Hadt, Roberto Alonso-Mori, Matthieu Chollet, James M. Glownia, Silke Nelson, Dimosthenis Sokaras, Kristjan Kunnus, Tim Brandt van Driel, Robert W. Hartsock, Kasper S. Kjaer, Clemens Weninger, Elisa Biasin, Leland B. Gee, Keith O. Hodgson, Britt Hedman, Uwe Bergmann, Edward I. Solomon, Kelly J. Gaffney
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b36cfbe98c1e409a802196ff2da67f18
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spelling	oai:doaj.org-article:b36cfbe98c1e409a802196ff2da67f182021-12-02T12:11:27ZShort-lived metal-centered excited state initiates iron-methionine photodissociation in ferrous cytochrome c10.1038/s41467-021-21423-w2041-1723https://doaj.org/article/b36cfbe98c1e409a802196ff2da67f182021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21423-whttps://doaj.org/toc/2041-1723The dissociation mechanism of the heme axial ligand in heme proteins is not yet fully understood. The authors investigate the photodissociation dynamics of the bond between heme Fe and methionine S in ferrous cytochrome c using femtosecond time-resolved X-ray solution scattering and X-ray emission spectroscopy, simultaneously tracking electronic and nuclear structure changes.Marco E. ReinhardMichael W. MaraThomas KrollHyeongtaek LimRyan G. HadtRoberto Alonso-MoriMatthieu CholletJames M. GlowniaSilke NelsonDimosthenis SokarasKristjan KunnusTim Brandt van DrielRobert W. HartsockKasper S. KjaerClemens WeningerElisa BiasinLeland B. GeeKeith O. HodgsonBritt HedmanUwe BergmannEdward I. SolomonKelly J. GaffneyNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Marco E. Reinhard Michael W. Mara Thomas Kroll Hyeongtaek Lim Ryan G. Hadt Roberto Alonso-Mori Matthieu Chollet James M. Glownia Silke Nelson Dimosthenis Sokaras Kristjan Kunnus Tim Brandt van Driel Robert W. Hartsock Kasper S. Kjaer Clemens Weninger Elisa Biasin Leland B. Gee Keith O. Hodgson Britt Hedman Uwe Bergmann Edward I. Solomon Kelly J. Gaffney Short-lived metal-centered excited state initiates iron-methionine photodissociation in ferrous cytochrome c
description	The dissociation mechanism of the heme axial ligand in heme proteins is not yet fully understood. The authors investigate the photodissociation dynamics of the bond between heme Fe and methionine S in ferrous cytochrome c using femtosecond time-resolved X-ray solution scattering and X-ray emission spectroscopy, simultaneously tracking electronic and nuclear structure changes.
format	article
author	Marco E. Reinhard Michael W. Mara Thomas Kroll Hyeongtaek Lim Ryan G. Hadt Roberto Alonso-Mori Matthieu Chollet James M. Glownia Silke Nelson Dimosthenis Sokaras Kristjan Kunnus Tim Brandt van Driel Robert W. Hartsock Kasper S. Kjaer Clemens Weninger Elisa Biasin Leland B. Gee Keith O. Hodgson Britt Hedman Uwe Bergmann Edward I. Solomon Kelly J. Gaffney
author_facet	Marco E. Reinhard Michael W. Mara Thomas Kroll Hyeongtaek Lim Ryan G. Hadt Roberto Alonso-Mori Matthieu Chollet James M. Glownia Silke Nelson Dimosthenis Sokaras Kristjan Kunnus Tim Brandt van Driel Robert W. Hartsock Kasper S. Kjaer Clemens Weninger Elisa Biasin Leland B. Gee Keith O. Hodgson Britt Hedman Uwe Bergmann Edward I. Solomon Kelly J. Gaffney
author_sort	Marco E. Reinhard
title	Short-lived metal-centered excited state initiates iron-methionine photodissociation in ferrous cytochrome c
title_short	Short-lived metal-centered excited state initiates iron-methionine photodissociation in ferrous cytochrome c
title_full	Short-lived metal-centered excited state initiates iron-methionine photodissociation in ferrous cytochrome c
title_fullStr	Short-lived metal-centered excited state initiates iron-methionine photodissociation in ferrous cytochrome c
title_full_unstemmed	Short-lived metal-centered excited state initiates iron-methionine photodissociation in ferrous cytochrome c
title_sort	short-lived metal-centered excited state initiates iron-methionine photodissociation in ferrous cytochrome c
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/b36cfbe98c1e409a802196ff2da67f18
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Short-lived metal-centered excited state initiates iron-methionine photodissociation in ferrous cytochrome c

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