A portable epigenetic switch for bistable gene expression in bacteria
Abstract We describe a portable epigenetic switch based on opvAB, a Salmonella enterica operon that undergoes bistable expression under DNA methylation control. A DNA fragment containing the opvAB promoter and the opvAB upstream regulatory region confers bistability to heterologous genes, yielding O...
Guardado en:
Autores principales: | David R. Olivenza, Hervé Nicoloff, María Antonia Sánchez-Romero, Ignacio Cota, Dan I. Andersson, Josep Casadesús |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
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Materias: | |
Acceso en línea: | https://doaj.org/article/b36d5c100fd74377906c0304d92d7e3f |
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