Role of specialized composition of SWI/SNF complexes in prostate cancer lineage plasticity
The differentiation of prostate adenocarcinoma to neuroendocrine prostate cancer (CRPC-NE) is a mechanism of resistance to androgen deprivation therapy. Here the authors show that SWI/SNF chromatin-remodeling complex is deregulated in CRPC-NE and that the complex interacts with different lineage spe...
Enregistré dans:
Auteurs principaux: | Joanna Cyrta, Anke Augspach, Maria Rosaria De Filippo, Davide Prandi, Phillip Thienger, Matteo Benelli, Victoria Cooley, Rohan Bareja, David Wilkes, Sung-Suk Chae, Paola Cavaliere, Noah Dephoure, Anne-Christine Uldry, Sophie Braga Lagache, Luca Roma, Sandra Cohen, Muriel Jaquet, Laura P. Brandt, Mohammed Alshalalfa, Loredana Puca, Andrea Sboner, Felix Feng, Shangqian Wang, Himisha Beltran, Tamara Lotan, Martin Spahn, Marianna Kruithof-de Julio, Yu Chen, Karla V. Ballman, Francesca Demichelis, Salvatore Piscuoglio, Mark A. Rubin |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2020
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/b36e0ab4d6324855a87fa9ba1ed5cc3e |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Patient derived organoids to model rare prostate cancer phenotypes
par: Loredana Puca, et autres
Publié: (2018) -
Mammalian SWI/SNF chromatin remodeler is essential for reductional meiosis in males
par: Debashish U. Menon, et autres
Publié: (2021) -
Structure of the yeast Swi/Snf complex in a nucleosome free state
par: Chengcheng Wang, et autres
Publié: (2020) -
Elucidating the regulatory mechanism of Swi1 prion in global transcription and stress responses
par: Zhiqiang Du, et autres
Publié: (2020) -
The SWI/SNF chromatin remodelling complex is required for maintenance of lineage specific enhancers
par: Burak H. Alver, et autres
Publié: (2017)