Observed birth prevalence of congenital anomalies among live births at a regional facility in KwaZulu Natal Province, South Africa.

Congenital disorders (CDs), defined as abnormalities in structure or function present at birth, are an important contributor to the disease burden in developing countries. The size and extent of the problem in South Africa (SA) are unknown due to the lack of recent, reliable, observed data on CDs. T...

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Autores principales:	Muhammad Zubayr Saib, Barnesh Lalloo Dhada, Colleen Aldous, Helen Louise Malherbe
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/b379d22918da44abbd84d3b128fdd659
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spelling	oai:doaj.org-article:b379d22918da44abbd84d3b128fdd6592021-12-02T20:15:17ZObserved birth prevalence of congenital anomalies among live births at a regional facility in KwaZulu Natal Province, South Africa.1932-620310.1371/journal.pone.0255456https://doaj.org/article/b379d22918da44abbd84d3b128fdd6592021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0255456https://doaj.org/toc/1932-6203Congenital disorders (CDs), defined as abnormalities in structure or function present at birth, are an important contributor to the disease burden in developing countries. The size and extent of the problem in South Africa (SA) are unknown due to the lack of recent, reliable, observed data on CDs. To address this empirical data gap, this study aimed to measure the birth prevalence of congenital anomalies (a sub-set of CDs) and to describe the pattern of these anomalies at a regional hospital in KwaZulu Natal (KZN), SA. A retrospective, observational, descriptive review of congenital anomalies diagnosed within the neonatal service at Edendale Hospital (EDH), KZN was undertaken between January and December 2018. All EDH in-house live births diagnosed and notified with congenital anomalies by discharge were included. Stillbirths, other pregnancy losses and out-born neonates were excluded. Data were actively collected from the birth register, neonatal admission register, and the individual paper-based surveillance tool developed by the National Department of Health. The in-facility birth prevalence rate for congenital anomalies was 15.57 per 1 000 live births. The most observed system was musculoskeletal (32%) followed by circulatory system anomalies (19%). When the observed birth prevalence rates of key congenital anomalies were compared with previously published, modelled South African data, no significant difference was found. This study responds to the paucity of birth prevalence data on CDs overall and offers evidence that obvious, structural CDs (congenital anomalies) need to be addressed in the SA public health system.Muhammad Zubayr SaibBarnesh Lalloo DhadaColleen AldousHelen Louise MalherbePublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 8, p e0255456 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Muhammad Zubayr Saib Barnesh Lalloo Dhada Colleen Aldous Helen Louise Malherbe Observed birth prevalence of congenital anomalies among live births at a regional facility in KwaZulu Natal Province, South Africa.
description	Congenital disorders (CDs), defined as abnormalities in structure or function present at birth, are an important contributor to the disease burden in developing countries. The size and extent of the problem in South Africa (SA) are unknown due to the lack of recent, reliable, observed data on CDs. To address this empirical data gap, this study aimed to measure the birth prevalence of congenital anomalies (a sub-set of CDs) and to describe the pattern of these anomalies at a regional hospital in KwaZulu Natal (KZN), SA. A retrospective, observational, descriptive review of congenital anomalies diagnosed within the neonatal service at Edendale Hospital (EDH), KZN was undertaken between January and December 2018. All EDH in-house live births diagnosed and notified with congenital anomalies by discharge were included. Stillbirths, other pregnancy losses and out-born neonates were excluded. Data were actively collected from the birth register, neonatal admission register, and the individual paper-based surveillance tool developed by the National Department of Health. The in-facility birth prevalence rate for congenital anomalies was 15.57 per 1 000 live births. The most observed system was musculoskeletal (32%) followed by circulatory system anomalies (19%). When the observed birth prevalence rates of key congenital anomalies were compared with previously published, modelled South African data, no significant difference was found. This study responds to the paucity of birth prevalence data on CDs overall and offers evidence that obvious, structural CDs (congenital anomalies) need to be addressed in the SA public health system.
format	article
author	Muhammad Zubayr Saib Barnesh Lalloo Dhada Colleen Aldous Helen Louise Malherbe
author_facet	Muhammad Zubayr Saib Barnesh Lalloo Dhada Colleen Aldous Helen Louise Malherbe
author_sort	Muhammad Zubayr Saib
title	Observed birth prevalence of congenital anomalies among live births at a regional facility in KwaZulu Natal Province, South Africa.
title_short	Observed birth prevalence of congenital anomalies among live births at a regional facility in KwaZulu Natal Province, South Africa.
title_full	Observed birth prevalence of congenital anomalies among live births at a regional facility in KwaZulu Natal Province, South Africa.
title_fullStr	Observed birth prevalence of congenital anomalies among live births at a regional facility in KwaZulu Natal Province, South Africa.
title_full_unstemmed	Observed birth prevalence of congenital anomalies among live births at a regional facility in KwaZulu Natal Province, South Africa.
title_sort	observed birth prevalence of congenital anomalies among live births at a regional facility in kwazulu natal province, south africa.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/b379d22918da44abbd84d3b128fdd659
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Observed birth prevalence of congenital anomalies among live births at a regional facility in KwaZulu Natal Province, South Africa.

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