Microchannelled alkylated chitosan sponge to treat noncompressible hemorrhages and facilitate wound healing

Developing effective treatments for noncompressible hemorrhages remains a challenge. Here the authors engineer alkylated chitosan sponges with highly interconnective microchannels and demonstrate anti-infective activity, as well as higher pro-coagulant, hemostatic and wound healing capacities compar...

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Autores principales:	Xinchen Du, Le Wu, Hongyu Yan, Zhuyan Jiang, Shilin Li, Wen Li, Yanli Bai, Hongjun Wang, Zhaojun Cheng, Deling Kong, Lianyong Wang, Meifeng Zhu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b37ce626c8a64381bec7cf7063c5061a
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spelling	oai:doaj.org-article:b37ce626c8a64381bec7cf7063c5061a2021-12-02T17:06:11ZMicrochannelled alkylated chitosan sponge to treat noncompressible hemorrhages and facilitate wound healing10.1038/s41467-021-24972-22041-1723https://doaj.org/article/b37ce626c8a64381bec7cf7063c5061a2021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24972-2https://doaj.org/toc/2041-1723Developing effective treatments for noncompressible hemorrhages remains a challenge. Here the authors engineer alkylated chitosan sponges with highly interconnective microchannels and demonstrate anti-infective activity, as well as higher pro-coagulant, hemostatic and wound healing capacities compared to clinically-used materials in rat and pig liver models.Xinchen DuLe WuHongyu YanZhuyan JiangShilin LiWen LiYanli BaiHongjun WangZhaojun ChengDeling KongLianyong WangMeifeng ZhuNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Xinchen Du Le Wu Hongyu Yan Zhuyan Jiang Shilin Li Wen Li Yanli Bai Hongjun Wang Zhaojun Cheng Deling Kong Lianyong Wang Meifeng Zhu Microchannelled alkylated chitosan sponge to treat noncompressible hemorrhages and facilitate wound healing
description	Developing effective treatments for noncompressible hemorrhages remains a challenge. Here the authors engineer alkylated chitosan sponges with highly interconnective microchannels and demonstrate anti-infective activity, as well as higher pro-coagulant, hemostatic and wound healing capacities compared to clinically-used materials in rat and pig liver models.
format	article
author	Xinchen Du Le Wu Hongyu Yan Zhuyan Jiang Shilin Li Wen Li Yanli Bai Hongjun Wang Zhaojun Cheng Deling Kong Lianyong Wang Meifeng Zhu
author_facet	Xinchen Du Le Wu Hongyu Yan Zhuyan Jiang Shilin Li Wen Li Yanli Bai Hongjun Wang Zhaojun Cheng Deling Kong Lianyong Wang Meifeng Zhu
author_sort	Xinchen Du
title	Microchannelled alkylated chitosan sponge to treat noncompressible hemorrhages and facilitate wound healing
title_short	Microchannelled alkylated chitosan sponge to treat noncompressible hemorrhages and facilitate wound healing
title_full	Microchannelled alkylated chitosan sponge to treat noncompressible hemorrhages and facilitate wound healing
title_fullStr	Microchannelled alkylated chitosan sponge to treat noncompressible hemorrhages and facilitate wound healing
title_full_unstemmed	Microchannelled alkylated chitosan sponge to treat noncompressible hemorrhages and facilitate wound healing
title_sort	microchannelled alkylated chitosan sponge to treat noncompressible hemorrhages and facilitate wound healing
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/b37ce626c8a64381bec7cf7063c5061a
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Microchannelled alkylated chitosan sponge to treat noncompressible hemorrhages and facilitate wound healing

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