Tracing tumorigenesis in a solid tumor model at single-cell resolution

Understanding tumour development at a granular level is a challenge in solid tumours. Here, the authors provide a cell atlas across tumour development in a genetic model of salivary gland squamous cell carcinoma using single-cell transcriptome and epitope profiling.

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Detalles Bibliográficos
Autores principales: Samantha D. Praktiknjo, Benedikt Obermayer, Qionghua Zhu, Liang Fang, Haiyue Liu, Hazel Quinn, Marlon Stoeckius, Christine Kocks, Walter Birchmeier, Nikolaus Rajewsky
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/b380cfe77d314a53a3df45bed0bf2bd8
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Sumario:Understanding tumour development at a granular level is a challenge in solid tumours. Here, the authors provide a cell atlas across tumour development in a genetic model of salivary gland squamous cell carcinoma using single-cell transcriptome and epitope profiling.