Size control in mammalian cells involves modulation of both growth rate and cell cycle duration
The size of cells fluctuates but there are limited experimental methods to measure live mammalian cell sizes. Here, the authors track single cell volume (FXm) over the cell cycle and generate a mathematical framework to compare size homeostasis in datasets ranging from bacteria to mammalian cells.
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Nature Portfolio
2018
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oai:doaj.org-article:b382a9086db94f9d839660b1465b4b842021-12-02T16:56:42ZSize control in mammalian cells involves modulation of both growth rate and cell cycle duration10.1038/s41467-018-05393-02041-1723https://doaj.org/article/b382a9086db94f9d839660b1465b4b842018-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05393-0https://doaj.org/toc/2041-1723The size of cells fluctuates but there are limited experimental methods to measure live mammalian cell sizes. Here, the authors track single cell volume (FXm) over the cell cycle and generate a mathematical framework to compare size homeostasis in datasets ranging from bacteria to mammalian cells.Clotilde CadartSylvain MonnierJacopo GrilliPablo J. SáezNishit SrivastavaRafaele AttiaEmmanuel TerriacBuzz BaumMarco Cosentino-LagomarsinoMatthieu PielNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018) |
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Science Q Clotilde Cadart Sylvain Monnier Jacopo Grilli Pablo J. Sáez Nishit Srivastava Rafaele Attia Emmanuel Terriac Buzz Baum Marco Cosentino-Lagomarsino Matthieu Piel Size control in mammalian cells involves modulation of both growth rate and cell cycle duration |
description |
The size of cells fluctuates but there are limited experimental methods to measure live mammalian cell sizes. Here, the authors track single cell volume (FXm) over the cell cycle and generate a mathematical framework to compare size homeostasis in datasets ranging from bacteria to mammalian cells. |
format |
article |
author |
Clotilde Cadart Sylvain Monnier Jacopo Grilli Pablo J. Sáez Nishit Srivastava Rafaele Attia Emmanuel Terriac Buzz Baum Marco Cosentino-Lagomarsino Matthieu Piel |
author_facet |
Clotilde Cadart Sylvain Monnier Jacopo Grilli Pablo J. Sáez Nishit Srivastava Rafaele Attia Emmanuel Terriac Buzz Baum Marco Cosentino-Lagomarsino Matthieu Piel |
author_sort |
Clotilde Cadart |
title |
Size control in mammalian cells involves modulation of both growth rate and cell cycle duration |
title_short |
Size control in mammalian cells involves modulation of both growth rate and cell cycle duration |
title_full |
Size control in mammalian cells involves modulation of both growth rate and cell cycle duration |
title_fullStr |
Size control in mammalian cells involves modulation of both growth rate and cell cycle duration |
title_full_unstemmed |
Size control in mammalian cells involves modulation of both growth rate and cell cycle duration |
title_sort |
size control in mammalian cells involves modulation of both growth rate and cell cycle duration |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/b382a9086db94f9d839660b1465b4b84 |
work_keys_str_mv |
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1718382763052105728 |