Size control in mammalian cells involves modulation of both growth rate and cell cycle duration

The size of cells fluctuates but there are limited experimental methods to measure live mammalian cell sizes. Here, the authors track single cell volume (FXm) over the cell cycle and generate a mathematical framework to compare size homeostasis in datasets ranging from bacteria to mammalian cells.

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Autores principales: Clotilde Cadart, Sylvain Monnier, Jacopo Grilli, Pablo J. Sáez, Nishit Srivastava, Rafaele Attia, Emmanuel Terriac, Buzz Baum, Marco Cosentino-Lagomarsino, Matthieu Piel
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/b382a9086db94f9d839660b1465b4b84
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spelling oai:doaj.org-article:b382a9086db94f9d839660b1465b4b842021-12-02T16:56:42ZSize control in mammalian cells involves modulation of both growth rate and cell cycle duration10.1038/s41467-018-05393-02041-1723https://doaj.org/article/b382a9086db94f9d839660b1465b4b842018-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05393-0https://doaj.org/toc/2041-1723The size of cells fluctuates but there are limited experimental methods to measure live mammalian cell sizes. Here, the authors track single cell volume (FXm) over the cell cycle and generate a mathematical framework to compare size homeostasis in datasets ranging from bacteria to mammalian cells.Clotilde CadartSylvain MonnierJacopo GrilliPablo J. SáezNishit SrivastavaRafaele AttiaEmmanuel TerriacBuzz BaumMarco Cosentino-LagomarsinoMatthieu PielNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Clotilde Cadart
Sylvain Monnier
Jacopo Grilli
Pablo J. Sáez
Nishit Srivastava
Rafaele Attia
Emmanuel Terriac
Buzz Baum
Marco Cosentino-Lagomarsino
Matthieu Piel
Size control in mammalian cells involves modulation of both growth rate and cell cycle duration
description The size of cells fluctuates but there are limited experimental methods to measure live mammalian cell sizes. Here, the authors track single cell volume (FXm) over the cell cycle and generate a mathematical framework to compare size homeostasis in datasets ranging from bacteria to mammalian cells.
format article
author Clotilde Cadart
Sylvain Monnier
Jacopo Grilli
Pablo J. Sáez
Nishit Srivastava
Rafaele Attia
Emmanuel Terriac
Buzz Baum
Marco Cosentino-Lagomarsino
Matthieu Piel
author_facet Clotilde Cadart
Sylvain Monnier
Jacopo Grilli
Pablo J. Sáez
Nishit Srivastava
Rafaele Attia
Emmanuel Terriac
Buzz Baum
Marco Cosentino-Lagomarsino
Matthieu Piel
author_sort Clotilde Cadart
title Size control in mammalian cells involves modulation of both growth rate and cell cycle duration
title_short Size control in mammalian cells involves modulation of both growth rate and cell cycle duration
title_full Size control in mammalian cells involves modulation of both growth rate and cell cycle duration
title_fullStr Size control in mammalian cells involves modulation of both growth rate and cell cycle duration
title_full_unstemmed Size control in mammalian cells involves modulation of both growth rate and cell cycle duration
title_sort size control in mammalian cells involves modulation of both growth rate and cell cycle duration
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/b382a9086db94f9d839660b1465b4b84
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