Tau enhances α-synuclein aggregation and toxicity in cellular models of synucleinopathy.
<h4>Background</h4>The simultaneous accumulation of different misfolded proteins in the central nervous system is a common feature in many neurodegenerative diseases. In most cases, co-occurrence of abnormal deposited proteins is observed in different brain regions and cell populations,...
Guardado en:
Autores principales: | Nahuai Badiola, Rita Machado de Oliveira, Federico Herrera, Cristina Guardia-Laguarta, Susana A Gonçalves, Marta Pera, Marc Suárez-Calvet, Jordi Clarimon, Tiago Fleming Outeiro, Alberto Lleó |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2011
|
Materias: | |
Acceso en línea: | https://doaj.org/article/b383f4ea139f4787b85f88b1e9deb2c4 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
α-Synuclein interacts directly but reversibly with psychosine: implications for α-synucleinopathies
por: Hazem Abdelkarim, et al.
Publicado: (2018) -
Synphilin-1 enhances α-synuclein aggregation in yeast and contributes to cellular stress and cell death in a Sir2-dependent manner.
por: Sabrina Büttner, et al.
Publicado: (2010) -
Autonomic ganglionic injection of α-synuclein fibrils as a model of pure autonomic failure α-synucleinopathy
por: Xue-Jing Wang, et al.
Publicado: (2020) -
Effects of the Toxic Metals Arsenite and Cadmium on α-Synuclein Aggregation In Vitro and in Cells
por: Emma Lorentzon, et al.
Publicado: (2021) -
EGCG impedes human Tau aggregation and interacts with Tau
por: Shweta Kishor Sonawane, et al.
Publicado: (2020)