Eosinophilic meningitis from bovine graft duraplasty treated without explantation

Aseptic cerebrospinal fluid eosinophilia is a rare complication associated with the use of bovine dural graft. It is thought to represent an inflammatory response to the foreign body. In previous case reports of children and adults, treatment has involved graft explantation, antibiotics or systemic...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Kersandra Begley, Jonathon Parkinson
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2022
Materias:	Aseptic meningitis Cerebrospinal fluid eosinophilia Bovine collagen dural graft Surgery RD1-811 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/b386d1836abd469eb534346ffc071a14
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:b386d1836abd469eb534346ffc071a14
record_format	dspace
spelling	oai:doaj.org-article:b386d1836abd469eb534346ffc071a142021-12-02T05:01:45ZEosinophilic meningitis from bovine graft duraplasty treated without explantation2214-751910.1016/j.inat.2021.101445https://doaj.org/article/b386d1836abd469eb534346ffc071a142022-03-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2214751921003571https://doaj.org/toc/2214-7519Aseptic cerebrospinal fluid eosinophilia is a rare complication associated with the use of bovine dural graft. It is thought to represent an inflammatory response to the foreign body. In previous case reports of children and adults, treatment has involved graft explantation, antibiotics or systemic corticosteroids. We describe the case of a 36 year old female who underwent posterior fossa craniotomy for tumour and repair with Durepair (Medtronic), a bovine collagen graft. One month later, she presented with aseptic eosinophilic meningitis. This was successfully treated with an extended course of oral dexamethasone, and no further surgery was required. She remained asymptomatic at 1 year follow up. A review of the literature on allergic eosinophilic meningitis as response to dural substitutes was conducted, with a focus on dural graft types and management.We conclude that aseptic eosinophilic meningitis is a rare complication after duraplasty, particularly in adults. CSF eosinophilia confirms that the pathology is not bacterial postoperative infection. Management with corticosteroids can be successful in treating this inflammatory reaction and does not require antibiotics or explantation of the allergenic material.Kersandra BegleyJonathon ParkinsonElsevierarticleAseptic meningitisCerebrospinal fluid eosinophiliaBovine collagen dural graftSurgeryRD1-811Neurology. Diseases of the nervous systemRC346-429ENInterdisciplinary Neurosurgery, Vol 27, Iss , Pp 101445- (2022)
institution	DOAJ
collection	DOAJ
language	EN
topic	Aseptic meningitis Cerebrospinal fluid eosinophilia Bovine collagen dural graft Surgery RD1-811 Neurology. Diseases of the nervous system RC346-429
spellingShingle	Aseptic meningitis Cerebrospinal fluid eosinophilia Bovine collagen dural graft Surgery RD1-811 Neurology. Diseases of the nervous system RC346-429 Kersandra Begley Jonathon Parkinson Eosinophilic meningitis from bovine graft duraplasty treated without explantation
description	Aseptic cerebrospinal fluid eosinophilia is a rare complication associated with the use of bovine dural graft. It is thought to represent an inflammatory response to the foreign body. In previous case reports of children and adults, treatment has involved graft explantation, antibiotics or systemic corticosteroids. We describe the case of a 36 year old female who underwent posterior fossa craniotomy for tumour and repair with Durepair (Medtronic), a bovine collagen graft. One month later, she presented with aseptic eosinophilic meningitis. This was successfully treated with an extended course of oral dexamethasone, and no further surgery was required. She remained asymptomatic at 1 year follow up. A review of the literature on allergic eosinophilic meningitis as response to dural substitutes was conducted, with a focus on dural graft types and management.We conclude that aseptic eosinophilic meningitis is a rare complication after duraplasty, particularly in adults. CSF eosinophilia confirms that the pathology is not bacterial postoperative infection. Management with corticosteroids can be successful in treating this inflammatory reaction and does not require antibiotics or explantation of the allergenic material.
format	article
author	Kersandra Begley Jonathon Parkinson
author_facet	Kersandra Begley Jonathon Parkinson
author_sort	Kersandra Begley
title	Eosinophilic meningitis from bovine graft duraplasty treated without explantation
title_short	Eosinophilic meningitis from bovine graft duraplasty treated without explantation
title_full	Eosinophilic meningitis from bovine graft duraplasty treated without explantation
title_fullStr	Eosinophilic meningitis from bovine graft duraplasty treated without explantation
title_full_unstemmed	Eosinophilic meningitis from bovine graft duraplasty treated without explantation
title_sort	eosinophilic meningitis from bovine graft duraplasty treated without explantation
publisher	Elsevier
publishDate	2022
url	https://doaj.org/article/b386d1836abd469eb534346ffc071a14
work_keys_str_mv	AT kersandrabegley eosinophilicmeningitisfrombovinegraftduraplastytreatedwithoutexplantation AT jonathonparkinson eosinophilicmeningitisfrombovinegraftduraplastytreatedwithoutexplantation
_version_	1718400788490878976

Eosinophilic meningitis from bovine graft duraplasty treated without explantation

Ejemplares similares