miRNA-200c-3p targets talin-1 to regulate integrin-mediated cell adhesion
Abstract The ability of integrins on the cell surface to mediate cell adhesion to the extracellular matrix ligands is regulated by intracellular signaling cascades. During this signaling process, the talin (TLN) recruited to integrin cytoplasmic tails plays the critical role of the major adaptor pro...
Enregistré dans:
Auteurs principaux: | Gideon Obeng, Eun Jeong Park, Michael G. Appiah, Eiji Kawamoto, Arong Gaowa, Motomu Shimaoka |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2021
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/b38ef06bfa9342939c29a80d19cbf190 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Quantitative single-protein imaging reveals molecular complex formation of integrin, talin, and kindlin during cell adhesion
par: Lisa S. Fischer, et autres
Publié: (2021) -
A computational analysis of the dynamic roles of talin, Dok1, and PIPKI for integrin activation.
par: Florian Geier, et autres
Publié: (2011) -
Structure of Rap1b bound to talin reveals a pathway for triggering integrin activation
par: Liang Zhu, et autres
Publié: (2017) -
MiRNA-200C expression in Fanconi anemia pathway functionally deficient lung cancers
par: Wenrui Duan, et autres
Publié: (2021) -
The mechanical response of talin
par: Mingxi Yao, et autres
Publié: (2016)