ADAR1-mediated regulation of melanoma invasion
In metastatic melanoma, ADAR1 is downregulated, facilitating proliferation. Here, the authors show an ADAR1-dependent and RNA-editing-independent regulation of melanoma invasion mediated by ITGB3 expression, which can be reversed when ITGB3 is blocked.
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Auteurs principaux: | Yael Nemlich, Erez Nissim Baruch, Michal Judith Besser, Einav Shoshan, Menashe Bar-Eli, Liat Anafi, Iris Barshack, Jacob Schachter, Rona Ortenberg, Gal Markel |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2018
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Sujets: | |
Accès en ligne: | https://doaj.org/article/b3931c919fb84915ae92ef05fa08880c |
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