Risk factors for diabetic autonomic cardiovascular neuropathy in children and adolescents with type 1 diabetes mellitus
Aim. To determine risk factors for diabetic autonomic cardiovascular neuropathy (DACN) and to optimize diagnostic procedures for children and adolescents with type 1 diabetes mellitus. Materials and methods. Heart rate variability (HRV) was assessed in 101 subjects with type 1 diabetes mellitus ag...
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| Auteurs principaux: | , , |
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| Format: | article |
| Langue: | EN RU |
| Publié: |
Endocrinology Research Centre
2013
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| Accès en ligne: | https://doaj.org/article/b396c294df404bbc9ee1e4a43e42810b |
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| Résumé: | Aim. To determine risk factors for diabetic autonomic cardiovascular neuropathy (DACN) and to optimize diagnostic procedures for children and adolescents with type 1 diabetes mellitus. Materials and methods. Heart rate variability (HRV) was assessed in 101 subjects with type 1 diabetes mellitus aged 5?17 y.o. in 4 functional tests. Subjects with 3 positive tests out 4 were considered positive for DACN. Results. Increased glycemic variability (9+ mmol/l per day), regular hypoglycemic events and late diabetes complications were found to be DACN risk factors in children and adolescents. Conclusions. A diagnostic algorithm for DACN in children and adolescents with type 1 diabetes mellitus based on orthostatic HRV variability assessment shows high sensitivity and efficiency. |
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