High-throughput single-cell rheology in complex samples by dynamic real-time deformability cytometry

Real-time deformability cytometry (RT-DC) is used for mechanical cell phenotyping but is limited to a single snapshot per cell and can only measure elastic modulus. Here the authors introduce dynamic RT-DC which can measure elasticity and viscosity in single cells by following dynamic cell shape cha...

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Autores principales:	Bob Fregin, Fabian Czerwinski, Doreen Biedenweg, Salvatore Girardo, Stefan Gross, Konstanze Aurich, Oliver Otto
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b397de1cf3cb42bea71a934781a7406b
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spelling	oai:doaj.org-article:b397de1cf3cb42bea71a934781a7406b2021-12-02T16:58:13ZHigh-throughput single-cell rheology in complex samples by dynamic real-time deformability cytometry10.1038/s41467-019-08370-32041-1723https://doaj.org/article/b397de1cf3cb42bea71a934781a7406b2019-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08370-3https://doaj.org/toc/2041-1723Real-time deformability cytometry (RT-DC) is used for mechanical cell phenotyping but is limited to a single snapshot per cell and can only measure elastic modulus. Here the authors introduce dynamic RT-DC which can measure elasticity and viscosity in single cells by following dynamic cell shape changes.Bob FreginFabian CzerwinskiDoreen BiedenwegSalvatore GirardoStefan GrossKonstanze AurichOliver OttoNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Bob Fregin Fabian Czerwinski Doreen Biedenweg Salvatore Girardo Stefan Gross Konstanze Aurich Oliver Otto High-throughput single-cell rheology in complex samples by dynamic real-time deformability cytometry
description	Real-time deformability cytometry (RT-DC) is used for mechanical cell phenotyping but is limited to a single snapshot per cell and can only measure elastic modulus. Here the authors introduce dynamic RT-DC which can measure elasticity and viscosity in single cells by following dynamic cell shape changes.
format	article
author	Bob Fregin Fabian Czerwinski Doreen Biedenweg Salvatore Girardo Stefan Gross Konstanze Aurich Oliver Otto
author_facet	Bob Fregin Fabian Czerwinski Doreen Biedenweg Salvatore Girardo Stefan Gross Konstanze Aurich Oliver Otto
author_sort	Bob Fregin
title	High-throughput single-cell rheology in complex samples by dynamic real-time deformability cytometry
title_short	High-throughput single-cell rheology in complex samples by dynamic real-time deformability cytometry
title_full	High-throughput single-cell rheology in complex samples by dynamic real-time deformability cytometry
title_fullStr	High-throughput single-cell rheology in complex samples by dynamic real-time deformability cytometry
title_full_unstemmed	High-throughput single-cell rheology in complex samples by dynamic real-time deformability cytometry
title_sort	high-throughput single-cell rheology in complex samples by dynamic real-time deformability cytometry
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/b397de1cf3cb42bea71a934781a7406b
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High-throughput single-cell rheology in complex samples by dynamic real-time deformability cytometry

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