A Bayesian mixture model for the analysis of allelic expression in single cells
Allele-specific expression at single-cell resolution can reveal stochastic and dynamic features of gene expression in greater detail. The authors propose scBASE, a soft zero-and-one inflated model that improves estimation of cellular allelic proportions by pooling information across cells.
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2019
|
| Subjects: | |
| Online Access: | https://doaj.org/article/b3986d791d71404d99354a6093a9a7be |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Be the first to leave a comment!