CircAnks1a in the spinal cord regulates hypersensitivity in a rodent model of neuropathic pain

Circular RNAs are non-coding RNAs that are enriched in the CNS, but their role in chronic pain is not known. Here the authors show that CircAnks1a in dorsal horn neurons contributes to pain-like hypersensitivity in a rodent model of neuropathic pain, via a VEGF mechanism.

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Autores principales:	Su-Bo Zhang, Su-Yan Lin, Meng Liu, Cui-Cui Liu, Huan-Huan Ding, Yang Sun, Chao Ma, Rui-Xian Guo, You-You Lv, Shao-Ling Wu, Ting Xu, Wen-Jun Xin
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b3ac0bb11f9b43cf9fde25c82e822ad5
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spelling	oai:doaj.org-article:b3ac0bb11f9b43cf9fde25c82e822ad52021-12-02T16:57:50ZCircAnks1a in the spinal cord regulates hypersensitivity in a rodent model of neuropathic pain10.1038/s41467-019-12049-02041-1723https://doaj.org/article/b3ac0bb11f9b43cf9fde25c82e822ad52019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12049-0https://doaj.org/toc/2041-1723Circular RNAs are non-coding RNAs that are enriched in the CNS, but their role in chronic pain is not known. Here the authors show that CircAnks1a in dorsal horn neurons contributes to pain-like hypersensitivity in a rodent model of neuropathic pain, via a VEGF mechanism.Su-Bo ZhangSu-Yan LinMeng LiuCui-Cui LiuHuan-Huan DingYang SunChao MaRui-Xian GuoYou-You LvShao-Ling WuTing XuWen-Jun XinNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Su-Bo Zhang Su-Yan Lin Meng Liu Cui-Cui Liu Huan-Huan Ding Yang Sun Chao Ma Rui-Xian Guo You-You Lv Shao-Ling Wu Ting Xu Wen-Jun Xin CircAnks1a in the spinal cord regulates hypersensitivity in a rodent model of neuropathic pain
description	Circular RNAs are non-coding RNAs that are enriched in the CNS, but their role in chronic pain is not known. Here the authors show that CircAnks1a in dorsal horn neurons contributes to pain-like hypersensitivity in a rodent model of neuropathic pain, via a VEGF mechanism.
format	article
author	Su-Bo Zhang Su-Yan Lin Meng Liu Cui-Cui Liu Huan-Huan Ding Yang Sun Chao Ma Rui-Xian Guo You-You Lv Shao-Ling Wu Ting Xu Wen-Jun Xin
author_facet	Su-Bo Zhang Su-Yan Lin Meng Liu Cui-Cui Liu Huan-Huan Ding Yang Sun Chao Ma Rui-Xian Guo You-You Lv Shao-Ling Wu Ting Xu Wen-Jun Xin
author_sort	Su-Bo Zhang
title	CircAnks1a in the spinal cord regulates hypersensitivity in a rodent model of neuropathic pain
title_short	CircAnks1a in the spinal cord regulates hypersensitivity in a rodent model of neuropathic pain
title_full	CircAnks1a in the spinal cord regulates hypersensitivity in a rodent model of neuropathic pain
title_fullStr	CircAnks1a in the spinal cord regulates hypersensitivity in a rodent model of neuropathic pain
title_full_unstemmed	CircAnks1a in the spinal cord regulates hypersensitivity in a rodent model of neuropathic pain
title_sort	circanks1a in the spinal cord regulates hypersensitivity in a rodent model of neuropathic pain
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/b3ac0bb11f9b43cf9fde25c82e822ad5
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CircAnks1a in the spinal cord regulates hypersensitivity in a rodent model of neuropathic pain

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