Identification of distinct maturation steps involved in human 40S ribosomal subunit biosynthesis
Ribosome synthesis is a complex multi-step process. Here the authors present a method that allows the efficient isolation and characterization of the preribosomal complexes formed along the entire ribosome synthesis pathway in human cells.
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Nature Portfolio
2020
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oai:doaj.org-article:b3c954f4e58948dc9782dcf8eafa89c72021-12-02T14:40:27ZIdentification of distinct maturation steps involved in human 40S ribosomal subunit biosynthesis10.1038/s41467-019-13990-w2041-1723https://doaj.org/article/b3c954f4e58948dc9782dcf8eafa89c72020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13990-whttps://doaj.org/toc/2041-1723Ribosome synthesis is a complex multi-step process. Here the authors present a method that allows the efficient isolation and characterization of the preribosomal complexes formed along the entire ribosome synthesis pathway in human cells.Blanca NietoSonia G. GasparGiulia MoriggiDimitri G. PestovXosé R. BusteloMercedes DosilNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-17 (2020) |
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Science Q |
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Science Q Blanca Nieto Sonia G. Gaspar Giulia Moriggi Dimitri G. Pestov Xosé R. Bustelo Mercedes Dosil Identification of distinct maturation steps involved in human 40S ribosomal subunit biosynthesis |
description |
Ribosome synthesis is a complex multi-step process. Here the authors present a method that allows the efficient isolation and characterization of the preribosomal complexes formed along the entire ribosome synthesis pathway in human cells. |
format |
article |
author |
Blanca Nieto Sonia G. Gaspar Giulia Moriggi Dimitri G. Pestov Xosé R. Bustelo Mercedes Dosil |
author_facet |
Blanca Nieto Sonia G. Gaspar Giulia Moriggi Dimitri G. Pestov Xosé R. Bustelo Mercedes Dosil |
author_sort |
Blanca Nieto |
title |
Identification of distinct maturation steps involved in human 40S ribosomal subunit biosynthesis |
title_short |
Identification of distinct maturation steps involved in human 40S ribosomal subunit biosynthesis |
title_full |
Identification of distinct maturation steps involved in human 40S ribosomal subunit biosynthesis |
title_fullStr |
Identification of distinct maturation steps involved in human 40S ribosomal subunit biosynthesis |
title_full_unstemmed |
Identification of distinct maturation steps involved in human 40S ribosomal subunit biosynthesis |
title_sort |
identification of distinct maturation steps involved in human 40s ribosomal subunit biosynthesis |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/b3c954f4e58948dc9782dcf8eafa89c7 |
work_keys_str_mv |
AT blancanieto identificationofdistinctmaturationstepsinvolvedinhuman40sribosomalsubunitbiosynthesis AT soniaggaspar identificationofdistinctmaturationstepsinvolvedinhuman40sribosomalsubunitbiosynthesis AT giuliamoriggi identificationofdistinctmaturationstepsinvolvedinhuman40sribosomalsubunitbiosynthesis AT dimitrigpestov identificationofdistinctmaturationstepsinvolvedinhuman40sribosomalsubunitbiosynthesis AT xoserbustelo identificationofdistinctmaturationstepsinvolvedinhuman40sribosomalsubunitbiosynthesis AT mercedesdosil identificationofdistinctmaturationstepsinvolvedinhuman40sribosomalsubunitbiosynthesis |
_version_ |
1718390319366537216 |