Identification of distinct maturation steps involved in human 40S ribosomal subunit biosynthesis

Ribosome synthesis is a complex multi-step process. Here the authors present a method that allows the efficient isolation and characterization of the preribosomal complexes formed along the entire ribosome synthesis pathway in human cells.

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Autores principales: Blanca Nieto, Sonia G. Gaspar, Giulia Moriggi, Dimitri G. Pestov, Xosé R. Bustelo, Mercedes Dosil
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/b3c954f4e58948dc9782dcf8eafa89c7
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spelling oai:doaj.org-article:b3c954f4e58948dc9782dcf8eafa89c72021-12-02T14:40:27ZIdentification of distinct maturation steps involved in human 40S ribosomal subunit biosynthesis10.1038/s41467-019-13990-w2041-1723https://doaj.org/article/b3c954f4e58948dc9782dcf8eafa89c72020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13990-whttps://doaj.org/toc/2041-1723Ribosome synthesis is a complex multi-step process. Here the authors present a method that allows the efficient isolation and characterization of the preribosomal complexes formed along the entire ribosome synthesis pathway in human cells.Blanca NietoSonia G. GasparGiulia MoriggiDimitri G. PestovXosé R. BusteloMercedes DosilNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Blanca Nieto
Sonia G. Gaspar
Giulia Moriggi
Dimitri G. Pestov
Xosé R. Bustelo
Mercedes Dosil
Identification of distinct maturation steps involved in human 40S ribosomal subunit biosynthesis
description Ribosome synthesis is a complex multi-step process. Here the authors present a method that allows the efficient isolation and characterization of the preribosomal complexes formed along the entire ribosome synthesis pathway in human cells.
format article
author Blanca Nieto
Sonia G. Gaspar
Giulia Moriggi
Dimitri G. Pestov
Xosé R. Bustelo
Mercedes Dosil
author_facet Blanca Nieto
Sonia G. Gaspar
Giulia Moriggi
Dimitri G. Pestov
Xosé R. Bustelo
Mercedes Dosil
author_sort Blanca Nieto
title Identification of distinct maturation steps involved in human 40S ribosomal subunit biosynthesis
title_short Identification of distinct maturation steps involved in human 40S ribosomal subunit biosynthesis
title_full Identification of distinct maturation steps involved in human 40S ribosomal subunit biosynthesis
title_fullStr Identification of distinct maturation steps involved in human 40S ribosomal subunit biosynthesis
title_full_unstemmed Identification of distinct maturation steps involved in human 40S ribosomal subunit biosynthesis
title_sort identification of distinct maturation steps involved in human 40s ribosomal subunit biosynthesis
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/b3c954f4e58948dc9782dcf8eafa89c7
work_keys_str_mv AT blancanieto identificationofdistinctmaturationstepsinvolvedinhuman40sribosomalsubunitbiosynthesis
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