Neutrophils drive endoplasmic reticulum stress-mediated apoptosis in cancer cells through arginase-1 release
Abstract Human neutrophils constitutively express high amounts of arginase-1, which depletes arginine from the surrounding medium and downregulates T-cell activation. Here, we have found that neutrophil arginase-1, released from activated human neutrophils or dead cells, induced apoptosis in cancer...
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Autores principales: | Rósula García-Navas, Consuelo Gajate, Faustino Mollinedo |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/b3ca417bc36d4ead837f65be523db8d4 |
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