Chromogastroduodenoscopy in Diagnostics of Ulcerative Lesions in Patients with Cardiovascular Pathology in Anemia

Rationale. Standard esophagogastroduodenoscopy does not always detect ‘plain’ defects of mucosa with fibrin in comorbid patients with anemia. It is known that irrigation of gastric mucosa with methylene blue solution makes the relief more distinct.Objective: to improve imaging of acute plain ulcers...

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Autores principales:	Anna A. Arkhipova, Aleksey V. Kuznetsov
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2019
Materias:	chromogastroduodenoscopy methylene blue ulcer erosion of anematized mucosa Science Q
Acceso en línea:	https://doaj.org/article/b3ce83e89a944a678466585eb00161e4
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spelling	oai:doaj.org-article:b3ce83e89a944a678466585eb00161e42021-11-23T06:14:42ZChromogastroduodenoscopy in Diagnostics of Ulcerative Lesions in Patients with Cardiovascular Pathology in Anemia2541-94202587-959610.29413/ABS.2019-4.1.15https://doaj.org/article/b3ce83e89a944a678466585eb00161e42019-04-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/1985https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596Rationale. Standard esophagogastroduodenoscopy does not always detect ‘plain’ defects of mucosa with fibrin in comorbid patients with anemia. It is known that irrigation of gastric mucosa with methylene blue solution makes the relief more distinct.Objective: to improve imaging of acute plain ulcers at anematized mucosa of stomach and duodenum using chromogastroduodenoscopy with methylene blue solution.Methods. Chromogastroduodenoscopy with 0.25% and 0.5% methylene blue solution was used in 28 patients (aged 53–86; 17 (60.7 %) women, 11 (39.3 %) men) hospitalized for acute and chronic cardiovascular pathology in anemia. The endoscopic examination was carried out in reanimation or intensive care units. The exclusion criterion was the patient’s refusal to participate in the study. The key outcome was identification of mucosa defects (erosion, ulcer).Results. Chromastroduodenoscopy with methylene blue allowed correct diagnosing of 5 patients (17.8 %) in which pathological processes could not be verified without contrasting. Improved visualization of mucosal defects during contrasting was obtained due to the following:– the colorant spreading over the surface of the mucous accumulates in folds and grooves, erosions, ulcers, thereby showing the configuration;– in stomach methylene blue does not color normal mucosa, but colors fibrin in the base of the defect. And in duodenum it colors mucosa and fibrin in the base of the ulcerative defect, while the edges of the defect are colored unevenly and are visualized as a rim during the imaging. No side effects were identified in the course of chromogastroduodenoscopy with methylene blue.Conclusion. Chromogastroduodenoscopy with methylene blue is of great practical importance, being an informative and simple method.Anna A. ArkhipovaAleksey V. KuznetsovScientific Сentre for Family Health and Human Reproduction Problemsarticlechromogastroduodenoscopymethylene blueulcererosion of anematized mucosaScienceQRUActa Biomedica Scientifica, Vol 4, Iss 1, Pp 102-106 (2019)
institution	DOAJ
collection	DOAJ
language	RU
topic	chromogastroduodenoscopy methylene blue ulcer erosion of anematized mucosa Science Q
spellingShingle	chromogastroduodenoscopy methylene blue ulcer erosion of anematized mucosa Science Q Anna A. Arkhipova Aleksey V. Kuznetsov Chromogastroduodenoscopy in Diagnostics of Ulcerative Lesions in Patients with Cardiovascular Pathology in Anemia
description	Rationale. Standard esophagogastroduodenoscopy does not always detect ‘plain’ defects of mucosa with fibrin in comorbid patients with anemia. It is known that irrigation of gastric mucosa with methylene blue solution makes the relief more distinct.Objective: to improve imaging of acute plain ulcers at anematized mucosa of stomach and duodenum using chromogastroduodenoscopy with methylene blue solution.Methods. Chromogastroduodenoscopy with 0.25% and 0.5% methylene blue solution was used in 28 patients (aged 53–86; 17 (60.7 %) women, 11 (39.3 %) men) hospitalized for acute and chronic cardiovascular pathology in anemia. The endoscopic examination was carried out in reanimation or intensive care units. The exclusion criterion was the patient’s refusal to participate in the study. The key outcome was identification of mucosa defects (erosion, ulcer).Results. Chromastroduodenoscopy with methylene blue allowed correct diagnosing of 5 patients (17.8 %) in which pathological processes could not be verified without contrasting. Improved visualization of mucosal defects during contrasting was obtained due to the following:– the colorant spreading over the surface of the mucous accumulates in folds and grooves, erosions, ulcers, thereby showing the configuration;– in stomach methylene blue does not color normal mucosa, but colors fibrin in the base of the defect. And in duodenum it colors mucosa and fibrin in the base of the ulcerative defect, while the edges of the defect are colored unevenly and are visualized as a rim during the imaging. No side effects were identified in the course of chromogastroduodenoscopy with methylene blue.Conclusion. Chromogastroduodenoscopy with methylene blue is of great practical importance, being an informative and simple method.
format	article
author	Anna A. Arkhipova Aleksey V. Kuznetsov
author_facet	Anna A. Arkhipova Aleksey V. Kuznetsov
author_sort	Anna A. Arkhipova
title	Chromogastroduodenoscopy in Diagnostics of Ulcerative Lesions in Patients with Cardiovascular Pathology in Anemia
title_short	Chromogastroduodenoscopy in Diagnostics of Ulcerative Lesions in Patients with Cardiovascular Pathology in Anemia
title_full	Chromogastroduodenoscopy in Diagnostics of Ulcerative Lesions in Patients with Cardiovascular Pathology in Anemia
title_fullStr	Chromogastroduodenoscopy in Diagnostics of Ulcerative Lesions in Patients with Cardiovascular Pathology in Anemia
title_full_unstemmed	Chromogastroduodenoscopy in Diagnostics of Ulcerative Lesions in Patients with Cardiovascular Pathology in Anemia
title_sort	chromogastroduodenoscopy in diagnostics of ulcerative lesions in patients with cardiovascular pathology in anemia
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2019
url	https://doaj.org/article/b3ce83e89a944a678466585eb00161e4
work_keys_str_mv	AT annaaarkhipova chromogastroduodenoscopyindiagnosticsofulcerativelesionsinpatientswithcardiovascularpathologyinanemia AT alekseyvkuznetsov chromogastroduodenoscopyindiagnosticsofulcerativelesionsinpatientswithcardiovascularpathologyinanemia
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Chromogastroduodenoscopy in Diagnostics of Ulcerative Lesions in Patients with Cardiovascular Pathology in Anemia

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