IL-13Rα2 uses TMEM219 in chitinase 3-like-1-induced signalling and effector responses

Chitinase 3-like 1 regulates cell death, inflammation and tissue remodelling via IL-13receptorα2. Here, the authors show that TMEM219 is a IL-13Rα2 co-receptor and modulates oxidant-induced apoptosis and lung injury, melanoma metastasis and TGF-β1 signalling, downstream of Chi3l1-IL-13Rα2.

Guardado en:

Detalles Bibliográficos
Autores principales:	Chang-Min Lee, Chuan Hua He, Adel M. Nour, Yang Zhou, Bing Ma, Jin Wook Park, Kyung Hee Kim, Charles Dela Cruz, Lokesh Sharma, Mahmoud L. Nasr, Yorgo Modis, Chun Geun Lee, Jack A. Elias
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b3d0784e7636416da889f0e12c206fac
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:b3d0784e7636416da889f0e12c206fac
record_format	dspace
spelling	oai:doaj.org-article:b3d0784e7636416da889f0e12c206fac2021-12-02T16:57:59ZIL-13Rα2 uses TMEM219 in chitinase 3-like-1-induced signalling and effector responses10.1038/ncomms127522041-1723https://doaj.org/article/b3d0784e7636416da889f0e12c206fac2016-09-01T00:00:00Zhttps://doi.org/10.1038/ncomms12752https://doaj.org/toc/2041-1723Chitinase 3-like 1 regulates cell death, inflammation and tissue remodelling via IL-13receptorα2. Here, the authors show that TMEM219 is a IL-13Rα2 co-receptor and modulates oxidant-induced apoptosis and lung injury, melanoma metastasis and TGF-β1 signalling, downstream of Chi3l1-IL-13Rα2.Chang-Min LeeChuan Hua HeAdel M. NourYang ZhouBing MaJin Wook ParkKyung Hee KimCharles Dela CruzLokesh SharmaMahmoud L. NasrYorgo ModisChun Geun LeeJack A. EliasNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Chang-Min Lee Chuan Hua He Adel M. Nour Yang Zhou Bing Ma Jin Wook Park Kyung Hee Kim Charles Dela Cruz Lokesh Sharma Mahmoud L. Nasr Yorgo Modis Chun Geun Lee Jack A. Elias IL-13Rα2 uses TMEM219 in chitinase 3-like-1-induced signalling and effector responses
description	Chitinase 3-like 1 regulates cell death, inflammation and tissue remodelling via IL-13receptorα2. Here, the authors show that TMEM219 is a IL-13Rα2 co-receptor and modulates oxidant-induced apoptosis and lung injury, melanoma metastasis and TGF-β1 signalling, downstream of Chi3l1-IL-13Rα2.
format	article
author	Chang-Min Lee Chuan Hua He Adel M. Nour Yang Zhou Bing Ma Jin Wook Park Kyung Hee Kim Charles Dela Cruz Lokesh Sharma Mahmoud L. Nasr Yorgo Modis Chun Geun Lee Jack A. Elias
author_facet	Chang-Min Lee Chuan Hua He Adel M. Nour Yang Zhou Bing Ma Jin Wook Park Kyung Hee Kim Charles Dela Cruz Lokesh Sharma Mahmoud L. Nasr Yorgo Modis Chun Geun Lee Jack A. Elias
author_sort	Chang-Min Lee
title	IL-13Rα2 uses TMEM219 in chitinase 3-like-1-induced signalling and effector responses
title_short	IL-13Rα2 uses TMEM219 in chitinase 3-like-1-induced signalling and effector responses
title_full	IL-13Rα2 uses TMEM219 in chitinase 3-like-1-induced signalling and effector responses
title_fullStr	IL-13Rα2 uses TMEM219 in chitinase 3-like-1-induced signalling and effector responses
title_full_unstemmed	IL-13Rα2 uses TMEM219 in chitinase 3-like-1-induced signalling and effector responses
title_sort	il-13rα2 uses tmem219 in chitinase 3-like-1-induced signalling and effector responses
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/b3d0784e7636416da889f0e12c206fac
work_keys_str_mv	AT changminlee il13ra2usestmem219inchitinase3like1inducedsignallingandeffectorresponses AT chuanhuahe il13ra2usestmem219inchitinase3like1inducedsignallingandeffectorresponses AT adelmnour il13ra2usestmem219inchitinase3like1inducedsignallingandeffectorresponses AT yangzhou il13ra2usestmem219inchitinase3like1inducedsignallingandeffectorresponses AT bingma il13ra2usestmem219inchitinase3like1inducedsignallingandeffectorresponses AT jinwookpark il13ra2usestmem219inchitinase3like1inducedsignallingandeffectorresponses AT kyungheekim il13ra2usestmem219inchitinase3like1inducedsignallingandeffectorresponses AT charlesdelacruz il13ra2usestmem219inchitinase3like1inducedsignallingandeffectorresponses AT lokeshsharma il13ra2usestmem219inchitinase3like1inducedsignallingandeffectorresponses AT mahmoudlnasr il13ra2usestmem219inchitinase3like1inducedsignallingandeffectorresponses AT yorgomodis il13ra2usestmem219inchitinase3like1inducedsignallingandeffectorresponses AT chungeunlee il13ra2usestmem219inchitinase3like1inducedsignallingandeffectorresponses AT jackaelias il13ra2usestmem219inchitinase3like1inducedsignallingandeffectorresponses
_version_	1718382410577477632

IL-13Rα2 uses TMEM219 in chitinase 3-like-1-induced signalling and effector responses

Ejemplares similares