Performance deficits of NK1 receptor knockout mice in the 5-choice serial reaction-time task: effects of d-amphetamine, stress and time of day.

Performance deficits of NK1 receptor knockout mice in the 5-choice serial reaction-time task: effects of d-amphetamine, stress and time of day.

<h4>Background</h4>The neurochemical status and hyperactivity of mice lacking functional substance P-preferring NK1 receptors (NK1R-/-) resemble abnormalities in Attention Deficit Hyperactivity Disorder (ADHD). Here we tested whether NK1R-/- mice express other core features of ADHD (impu...

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Autores principales: Ting Carrie Yan, Julia A Dudley, Ruth K Weir, Ewelina M Grabowska, Yolanda Peña-Oliver, Tamzin L Ripley, Stephen P Hunt, David N Stephens, S Clare Stanford
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/b3d150a334c24b3588694dd161873f01
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