A mouse tissue transcription factor atlas

While we have abundant data for transcription factor (TF) binding sites and TF expression at the mRNA level, our knowledge of TFs at the protein level and their DNA-binding activities is sparser. Here, the authors address this by using the catTFRE approach to profile active TFs in 24 adult and 8 fet...

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Autores principales: Quan Zhou, Mingwei Liu, Xia Xia, Tongqing Gong, Jinwen Feng, Wanlin Liu, Yang Liu, Bei Zhen, Yi Wang, Chen Ding, Jun Qin
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/b3d82a2891cc40c598ae49e6516fde86
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spelling oai:doaj.org-article:b3d82a2891cc40c598ae49e6516fde862021-12-02T17:06:27ZA mouse tissue transcription factor atlas10.1038/ncomms150892041-1723https://doaj.org/article/b3d82a2891cc40c598ae49e6516fde862017-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms15089https://doaj.org/toc/2041-1723While we have abundant data for transcription factor (TF) binding sites and TF expression at the mRNA level, our knowledge of TFs at the protein level and their DNA-binding activities is sparser. Here, the authors address this by using the catTFRE approach to profile active TFs in 24 adult and 8 fetal mouse tissues, and presenting the TF networks in major mouse organs.Quan ZhouMingwei LiuXia XiaTongqing GongJinwen FengWanlin LiuYang LiuBei ZhenYi WangChen DingJun QinNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Quan Zhou
Mingwei Liu
Xia Xia
Tongqing Gong
Jinwen Feng
Wanlin Liu
Yang Liu
Bei Zhen
Yi Wang
Chen Ding
Jun Qin
A mouse tissue transcription factor atlas
description While we have abundant data for transcription factor (TF) binding sites and TF expression at the mRNA level, our knowledge of TFs at the protein level and their DNA-binding activities is sparser. Here, the authors address this by using the catTFRE approach to profile active TFs in 24 adult and 8 fetal mouse tissues, and presenting the TF networks in major mouse organs.
format article
author Quan Zhou
Mingwei Liu
Xia Xia
Tongqing Gong
Jinwen Feng
Wanlin Liu
Yang Liu
Bei Zhen
Yi Wang
Chen Ding
Jun Qin
author_facet Quan Zhou
Mingwei Liu
Xia Xia
Tongqing Gong
Jinwen Feng
Wanlin Liu
Yang Liu
Bei Zhen
Yi Wang
Chen Ding
Jun Qin
author_sort Quan Zhou
title A mouse tissue transcription factor atlas
title_short A mouse tissue transcription factor atlas
title_full A mouse tissue transcription factor atlas
title_fullStr A mouse tissue transcription factor atlas
title_full_unstemmed A mouse tissue transcription factor atlas
title_sort mouse tissue transcription factor atlas
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/b3d82a2891cc40c598ae49e6516fde86
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